Visible Light-Induced Regioselective Cycloaddition of Benzoyl Azides and Alkenes To Yield Oxazolines

被引：29

作者：

Bellotti, Peter ^{[1
]}

Brocus, Julien ^{[2
]}

El Orf, Fatima ^{[2
]}

Selkti, Mohamed ^{[3
]}

Koenig, Burkhard ^{[1
]}

Belmont, Philippe ^{[2
]}

Brachet, Etienne ^{[2
]}

机构：

[1] Univ Regensburg, Fac Chem & Pharm, Inst Organ Chem, Univ Str 31, D-93053 Regensburg, Germany

[2] USPC, Univ Paris Descartes, Fac Pharm Paris, COMETE,CNRS,UMR 8638, 4 Ave Observ, F-75006 Paris, France

[3] USPC, Univ Paris Descartes, Fac Pharm Paris, LCRB,CNRS,UMR 8015, 4 Ave Observ, F-75006 Paris, France

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 84卷 / 10期

关键词：

OLEFIN AZIRIDINATION; ACYL AZIDES; PHOTOREDOX; PHOTOCHEMISTRY; ACYLNITRENES; GENERATION; CATALYSIS; INDOLE; ACID;

D O I：

10.1021/acs.joc.9b00568

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Visible light catalysis allows the regioselective synthesis of oxazolines in high yields. The mild photosensitized manifold leverages the intermolecular formation of oxazolines with a wide functional group tolerance on both benzoyl azides and alkenes partners. Mechanistic investigations suggest the sensitization of the azide moiety as the key activation step.

引用

页码：6278 / 6285

页数：8

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