The use of tungsten disulfide dots as highly selective, fluorescent probes for analysis of nitrofurazone

Tungsten disulfide (WS2) is a two-dimensional transition metal dichalcogenide, which is of particular interest because it has highly anisotropic bonding, which leads to strongly anisotropic electrical and mechanical properties. Thus, in this work, a simple hydrothermal process was developed to produce photoluminescence from WS2 dots. This was achieved in the presence of sodium tungstate and reduced L-glutathione; the emitted fluorescence produced a quantum yield as high as 0.066. The WS2 dots and the associated fluorescence were investigated with the use of transmission electron microscopy, atomic force microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared and UV-vis spectroscopies. The WS2 dots were used as a fluorescent probe to analyze nitrofurazone (NFZ). The associated fluorescence resonance energy transfer (FRET) mechanism was also investigated and the emitted fluorescence was found to be linear in the range of 0.17-166 mu mol L-1 with a detection limit of 0.055 mu mol L-1. The proposed method was successfully applied for analysis of NFZ in nasal drops and water samples. (C) 2015 Elsevier B.V. All rights reserved.