Self-assembling urea-based peptidomimetics: A simple one-step synthesis and crystal structure of core beta-alanyl ureylene retro-bispeptides (MeO-A(aa)-[NH-CO-NH]-CH2-CH2-CO-NH-A(aa)-OMe; A(aa)=amino acid A)

被引：19
作者：
Ranganathan, D
Kurur, S
Madhusudanan, KP
Karle, IL
机构：
[1] CENT DRUG RES INST,LUCKNOW 226001,UTTAR PRADESH,INDIA
[2] USN,RES LAB,STRUCT MATTER LAB,WASHINGTON,DC 20375
来源：
TETRAHEDRON LETTERS | 1997年 / 38卷 / 26期
关键词：
D O I：
10.1016/S0040-4039(97)00960-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel family of urea-based peptidomimetics containing beta-alanyl unit at the core has been synthesized by a simple one-step procedure. Solid state structures of some representative examples have showm self-assembly into highly ordered extended hydrogen-bonded chains and ribbons with modest NLO activity. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码：4659 / 4662
页数：4
相关论文
共 21 条
123