High-Q polymer resonators with spatially controlled photo-functionalization for biosensing applications

被引:14
作者
Beck, Torsten [1 ]
Mai, Martin [1 ]
Grossmann, Tobias [1 ,2 ]
Wienhold, Tobias [2 ]
Hauser, Mario [1 ]
Mappes, Timo [2 ]
Kalt, Heinz [1 ]
机构
[1] KIT, Inst Appl Phys, D-76128 Karlsruhe, Germany
[2] KIT, Inst Microstruct Technol, D-76128 Karlsruhe, Germany
关键词
STREPTAVIDIN; SENSORS;
D O I
10.1063/1.4798533
中图分类号
O59 [应用物理学];
学科分类号
摘要
We demonstrate the applicability of polymeric whispering gallery mode resonators fabricated on silicon as biosensors. Optical measurements on the passive resonators in the visible spectral range yield Q-factors as high as 1.3 x 10(7). Local, covalent surface functionalization, is achieved by spatially controlled UV-exposure of a derivative of the photoreactive crosslinker benzophenone. Protein detection is shown using the specific binding of the biotin-streptavidin system. (C) 2013 American Institute of Physics. [http://dx.doi.org/10.1063/1.4798533]
引用
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页数:3
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