Mixed metal MgO-ZrO2 nanoparticle-catalyzed O-tert-Boc protection of alcohols and phenols under solvent-free conditions

被引：50

作者：

Gawande, Manoj B. ^{[1
]}

Shelke, Sharad N. ^{[2
]}

Branco, Paula S. ^{[1
]}

Rathi, Anuj ^{[3
]}

Pandey, Rajesh K. ^{[4
]}

机构：

[1] Univ Nova Lisboa, Dept Quim, Fac Cienciase Tecnol, REQUIMTE, P-1200 Lisbon, Portugal

[2] SSGM Coll, Dept Chem, Kopargaon 423601, MH, India

[3] Jubilant Chemsys Ltd, New Delhi 201301, Noida, India

[4] Marquette Univ, Dept Chem, Milwaukee, WI 53233 USA

来源：

APPLIED ORGANOMETALLIC CHEMISTRY | 2012年 / 26卷 / 08期

关键词：

O-tert-butoxycarbonylation; phenol and alcohol; mixed metal oxides; nanoparticles; solvent-free; reusable and recyclable; BUTYL DICARBONATE; HYDROXY COMPOUNDS; HIGHLY EFFICIENT; BUTOXYCARBONYLATION; AMINES; CARBONATES; ACID; ANHYDRIDES; HALIDES;

D O I：

10.1002/aoc.2846

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An environmentally benign method for O-tert-Boc protection of alcohols and phenols catalyzed by MgOZrO2 nanoparticles under solvent-free conditions is described. A variety of phenols, alcohols (aliphatic and aromatic) were converted to corresponding O-tert-Boc products in good to excellent yield (5095%). The present protocol is expedient, simple, and efficient under solvent-free conditions. The MgOZrO2 Nps are easily prepared from inexpensive precursors, and are reusable, recyclable and chemoselective. Copyright (c) 2012 John Wiley & Sons, Ltd.

引用

页码：395 / 400

页数：6

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