Structure and mechanism of the RNA polymerase II transcription machinery

被引：377
作者：
Hahn, S
机构：
[1] Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA
[2] Howard Hughes Med Inst, Seattle, WA 98109 USA
来源：
NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2004年 / 11卷 / 05期
关键词：
D O I：
10.1038/nsmb763
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Advances in structure determination of the bacterial and eukaryotic transcription machinery have led to a marked increase in the understanding of the mechanism of transcription. Models for the specific assembly of the RNA polymerase II transcription machinery at a promoter, conformational changes that occur during initiation of transcription, and the mechanism of initiation are discussed in light of recent developments.
引用
收藏
页码：394 / 403
页数：10
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