The 2011-12 pilot European Sentinel Registry of Transcatheter Aortic Valve Implantation: in-hospital results in 4,571 patients

被引:147
作者
Di Mario, Carlo [1 ]
Eltchaninoff, Helene [2 ]
Moat, Neil [1 ]
Goicolea, Javier [3 ]
Ussia, Gian Paolo [4 ]
Kala, Petr [5 ]
Wenaweser, Peter [6 ]
Zembala, Marian [7 ]
Nickenig, Georg [8 ]
Barrero, Eduardo Alegria [1 ]
Snow, Thomas [1 ]
Iung, Bernard [9 ]
Zamorano, Pepe [10 ]
Schuler, Gerhard [11 ]
Corti, Roberto [12 ]
Alfieri, Ottavio [13 ]
Prendergast, Bernard [14 ]
Ludman, Peter [15 ]
Windecker, Stephan [6 ]
Sabate, Manel [16 ]
Gilard, Martine [17 ]
Witowski, Adam [18 ]
Danenberg, Haim [19 ]
Schroeder, Erwin [20 ]
Romeo, Francesco [21 ]
Macaya, Carlos [22 ]
Derumeaux, Genevieve [23 ]
Maggioni, Aldo [24 ]
Tavazzi, Luigi [25 ,26 ]
机构
[1] Royal Brompton Hosp, London SW3 6NP, England
[2] Univ Hosp, Rouen, France
[3] Hosp Univ Puerta de Hierro, Madrid, Spain
[4] Univ Catania, Ferrarotto Hosp, Catania, Italy
[5] Masaryk Univ, Univ Hosp Brno, Brno, Czech Republic
[6] Univ Hosp Bern, CH-3010 Bern, Switzerland
[7] Silesian Ctr Heart Dis, Zabrze, Poland
[8] Univ Hosp, Bonn, Germany
[9] Hop Bichat Claude Bernard, F-75877 Paris, France
[10] Hosp Univ Ramon y Cajall, Madrid, Spain
[11] Herzzentrum Leipzig, Abt Kardiol & Angiol, Leipzig, Germany
[12] Univ Zurich Hosp, CH-8091 Zurich, Switzerland
[13] Osped San Raffaele Milan, Milan, Italy
[14] John Radcliffe Hosp, Oxford OX3 9DU, England
[15] Queen Elizabeth Hosp, Birmingham B15 2TH, W Midlands, England
[16] Hosp Clin Barcelona, Thorax Inst, Barcelona, Spain
[17] CHU Brest, F-29285 Brest, France
[18] Inst Cardiol, Warsaw, Poland
[19] Hadassah Hebrew Univ Med Ctr, Jerusalem, Israel
[20] UCL Mt Godinne, Yvoir, Belgium
[21] Univ Roma Tor Vergata, Rome, Italy
[22] Clin San Carlos Univ Hosp, Madrid, Spain
[23] Univ Lyon, Lyon, France
[24] ANMCO Res Ctr, Florence, Italy
[25] Ettore Sansavini Hlth Sci Fdn, GVM Hosp Care, Cotignola, Italy
[26] Ettore Sansavini Hlth Sci Fdn, GVM Hosp Res, Cotignola, Italy
关键词
aortic valve disease; TAVI; valvular heart disease; OUTCOMES; STENOSIS; COREVALVE;
D O I
10.4244/EIJV8I12A209
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims: The aim of this prospective multinational registry is to assess and identify predictors of in-hospital outcome and complications of contemporary TAVI practice. Methods and results: The Transcatheter Valve Treatment Sentinel Pilot Registry is a prospective independent consecutive collection of individual patient data entered into a web-based case record form (CRF) or transferred from compatible national registries. A total of 4,571 patients underwent TAVI between January 2011 and May 2012 in 137 centres of 10 European countries. Average age was 81.4+/-7.1 years with equal representation of the two sexes. Logistic EuroSCORE (20.2+/-13.3), access site (femoral approach: 74.2%), type of anaesthesia and duration of hospital stay (9.3+/-8.1 days) showed wide variations among the participating countries. In-hospital mortality (7.4%), stroke (1.8%), myocardial infarction (0.9%), major vascular complications (3.1%) were similar in the SAPIEN XT and CoreValve (p=0.15). Mortality was lower in transfemoral (5.9%) than in transapical (12.8%) and other access routes (9.7%; p<0.01). Advanced age, high logistic EuroSCORE, pre-procedural >= grade 2 mitral regurgitation and deployment failure predicted higher mortality at multivariate analysis. Conclusions: Increased operator experience and the refinement of valve types and delivery catheters may explain the lower rate of mortality, stroke and vascular complications than in historical studies and registries.
引用
收藏
页码:1362 / 1371
页数:10
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