Effect of low level microwave radiation exposure on cognitive function and oxidative stress in rats

被引:3
作者
Deshmukh, Pravin Suryakantrao [1 ]
Banerjee, Basu Dev [1 ]
Abegaonkar, Mahesh Pandurang [4 ]
Megha, Kanu [1 ]
Ahmed, Rafat Sultana [1 ]
Tripathi, Ashok Kumar [1 ]
Mediratta, Pramod Kumari [2 ,3 ]
机构
[1] Univ Coll Med Sci, Dept Biochem, Environm Biochem & Mol Biol Lab, Delhi 110095, India
[2] Univ Coll Med Sci, Dept Pharmacol, Delhi 110095, India
[3] Univ Delhi, GTB Hosp, Delhi 110095, India
[4] Indian Inst Technol, CARE, New Delhi 110016, India
关键词
Cognitive function; Microwave exposure; Oxidative stress; 900; MHz; MOBILE PHONES; DNA BREAKS; IMPAIRMENT; BRAIN;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Use of wireless communicating devices is increasing at an exponential rate in present time and is raising serious concerns about possible adverse effects of microwave (MW) radiation emitted from these devices on human health. The present study aimed to evaluate the effects of 900 MHz MW radiation exposure on cognitive function and oxidative stress in blood of Fischer rats. Animals were divided into two groups (6 animals/group): Group I (MW-exposed) and Group II (Sham-exposed). Animals were subjected to MW exposure (Frequency 900 MHz; specific absorption rate 8.4738 x 10(-5) W/kg) in Gigahertz transverse electromagnetic cell (GTEM) for 30 days (2 h/day, 5 days/week). Subsequently, cognitive function and oxidative stress parameters were examined for each group. Results showed significant impairment in cognitive function and increase in oxidative stress, as evidenced by the increase in levels of MDA (a marker of lipid peroxidation) and protein carbonyl (a marker of protein oxidation) and unaltered GSH content in blood. Thus, the study demonstrated that low level MW radiation had significant effect on cognitive function and was also capable of leading to oxidative stress.
引用
收藏
页码:114 / 119
页数:6
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