Thermal induced intramolecular [2+2] cycloaddition of allene-ACPs

被引：32

作者：

Chen, Kai ^{[1
,2
]}

Sun, Run ^{[1
,2
]}

Xu, Qin ^{[1
,2
]}

Wei, Yin ^{[3
]}

Shi, Min ^{[1
,2
,3
]}

机构：

[1] E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China

[2] E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

[3] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2013年 / 11卷 / 24期

基金：

中国国家自然科学基金;

关键词：

UNIQUE TETRASUBSTITUTED ALKENE; MGI2-MEDIATED RING EXPANSIONS; ACID-MEDIATED CYCLOADDITION; TETHERED ALKYLIDENECYCLOPROPANES; CYCLOBUTANE DERIVATIVES; PYRROLIDINE SKELETONS; BOND-CLEAVAGE; METHYLENECYCLOPROPANES; EFFICIENT; LEWIS;

D O I：

10.1039/c3ob40911b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile synthetic method for preparation of bicyclo[4.2.0] nitrogen heterocycles has been developed via a thermal induced intramolecular [2 + 2] cycloaddition reaction of allene-ACPs. The DFT calculations indicate that this intramolecular cycloaddition proceeds in a concerted manner and a strained small ring is essential.

引用

页码：3949 / 3953

页数：5

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