Cushing's syndrome

被引:989
作者
Newell-Price, J [1 ]
Bertagna, X
Grossman, AB
Nieman, LK
机构
[1] Univ Sheffield, No Gen Hosp, Div Clin Sci, Sheffield S5 7AU, S Yorkshire, England
[2] Royal Hallamshire Hosp, Dept Endocrinol, Sheffield S10 2JF, S Yorkshire, England
[3] Univ Paris 05, Fac Med Rene Descartes, INSERM, U567,Inst Cochin,Dept Endocrinol, Paris, France
[4] Barts & London Queen Marys Sch Med & Dent, William Harvey Res Inst, Dept Endocrinol, London, England
[5] NICHHD, Reprod Endocrinol & Med Branch, NIH, Bethesda, MD 20891 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S0140-6736(06)68699-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cushing's syndrome results from lengthy and inappropriate exposure to excessive glucocorticoids. Untreated, it has significant morbidity and mortality. The syndrome remains a challenge to diagnose and manage. Here, we review the current understanding of pathogenesis, clinical features, diagnostic, and differential diagnostic approaches. We provide diagnostic algorithms and recommendations for management.
引用
收藏
页码:1605 / 1617
页数:13
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