Prediction of cortical bone elastic constants by a two-level micromechanical model using a generalized self-consistent method

被引:40
作者
Dong, X. Neil [1 ]
Guo, X. Edward [1 ]
机构
[1] Columbia Univ, Dept Biomed Engn, Bone Bioengn Lab, New York, NY 10027 USA
来源
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME | 2006年 / 128卷 / 03期
关键词
D O I
10.1115/1.2187039
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A two-level micromechanical model of cortical bone based on a generalized self-consistent method was developed to take into consideration the transversely isotropic elasticity of mangy microstructural features in cortical bone, including Haversian canals, resorption cavities, and osteonal and interstitial lamellae. In the first level, a single osteon was modeled as a two-phase composite such that Haversian canals were represented by elongated pores while the surrounding osteonal lamellae were considered as matrix. In the second level, osteons and resorption cavities were modeled as multiple inclusions while interstitial lamellae were regarded as matrix. The predictions of cortical bone elasticity from this two-level micromechanical model were mostly in agreement with experimental data for the dependence of transversely isotropic elasticity of human femoral cortical bone on porosity. However, variation in cortical bone elastic constants was greater in experimental data than in model predictions. This could be attributed to variations in the elastic properties of microstructural features in cortical bone. The present micromechanical model of cortical bone will be useful in understanding the contribution of cortical bone porosity to femoral neck fractures.
引用
收藏
页码:309 / 316
页数:8
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