Boswellic acids: a group of medicinally important compounds

被引:137
|
作者
Shah, Bhahwal Ali [1 ]
Qazi, Ghulam Nabi [1 ]
Taneja, Subhash Chandra [1 ]
机构
[1] CSIR, Indian Inst Integrat Med, Jammu 180001, India
关键词
NF-KAPPA-B; PERFORMANCE LIQUID-CHROMATOGRAPHY; ACETATE INDUCES DIFFERENTIATION; PENTACYCLIC TRITERPENIC ACIDS; INDUCED CA2+ MOBILIZATION; BURSERACEAE GUM RESIN; ACETYL-11-KETO-BETA-BOSWELLIC ACID; IN-VITRO; INHIBITORY-ACTIVITY; SERRATA EXTRACT;
D O I
10.1039/b809437n
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review, containing over 276 references, covers the progress made in the chemistry and bioactivity of this important group of triterpenoids. Though initially known for their anti-inflammatory and anti-arthritic activities through a unique 5-LO inhibition mechanism, boswellic acids have recently attained significance due to their anti-cancer properties. The phytochemistry and chemical modifications, including mechanism of action, are discussed.
引用
收藏
页码:72 / 89
页数:18
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