A Novel Ratiometric Two-Photon Fluorescent Probe for the Detection of Biothiols in Solution and Imaging of Living Cells

被引：32
|
作者：
Wu, Qing-Qing [1 ]
Xiao, Zu-Feng [1 ]
Du, Xiao-Jiao [2 ,3 ]
Song, Qin-Hua [1 ]
机构：
[1] Univ Sci & Technol China, Joint Lab Green Synthet Chem, Dept Chem, Hefei 230026, Peoples R China
[2] Univ Sci & Technol China, CAS Key Lab Brain Funct & Dis, Hefei 230027, Anhui, Peoples R China
[3] Univ Sci & Technol China, Sch Life Sci, Hefei 230027, Anhui, Peoples R China
来源：
CHEMISTRY-AN ASIAN JOURNAL | 2013年 / 8卷 / 11期
基金：
中国国家自然科学基金;
关键词：
cellular imaging; fluorescent probes; intramolcular charge transfer; quinolines; thiols; LARGE STOKES SHIFT; TURN-ON PROBE; THIOL PROBE; SELECTIVE DETECTION; CYSTEINE; GLUTATHIONE; HOMOCYSTEINE; QUANTIFICATION; NAPHTHALIMIDE; RECOGNITION;
D O I：
10.1002/asia.201300491
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
What a great response: A novel fluorescent probe for biothiols has been constructed based on the Michael addition. The adducts of the probe with thiols possess an intramolecular charge transfer character in their excited states, and detection of biothiols reveals a ratiometric spectral response. Furthermore, biothiols were detected through cell imaging under both one-photon and two-photon excitations. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：2564 / 2568
页数：5
相关论文
共 50 条
  • [31] Monitoring biothiols dynamics in living cells by ratiometric fluorescent gold carbon dots
    Xie, Xiaoxue
    Peng, Zhenqi
    Wang, Ziqi
    Hua, Xinyi
    Wang, Zhifang
    Deng, Keqin
    Yang, Xiumei
    Huang, Haowen
    Liu, Xuanyong
    TALANTA, 2020, 218
  • [32] A cysteamine-selective two-photon fluorescent probe for ratiometric bioimaging
    Sarkar, Avik R.
    Heo, Cheol Ho
    Kim, Eunjin
    Lee, Hyo Won
    Singh, Hardev
    Kim, Jeong Jin
    Kang, Hyuk
    Kang, Chulhun
    Kim, Hwan Myung
    CHEMICAL COMMUNICATIONS, 2015, 51 (12) : 2407 - 2410
  • [33] A novel ratiometric AIE-based fluorescent probe for specific detection of Hcy/Cys and imaging of living cells in vivo
    Lv, Hong-Min
    Jiang, Zi-Ke
    Wang, Jing
    Wang, Tao
    Zhang, Xiao-Nan
    Hu, Yi-Meng
    Ma, Yan-Yan
    NEW JOURNAL OF CHEMISTRY, 2021, 45 (41) : 19521 - 19530
  • [34] A novel Boranil-based turn-on fluorescent probe for imaging of biothiols in living cells
    Ren, Aishan
    Zhu, Dongjian
    Luo, Yanghe
    JOURNAL OF MOLECULAR STRUCTURE, 2020, 1209
  • [35] A two-photon ratiometric fluorescent probe for highly selective sensing of mitochondrial cysteine in live cells
    Fan, Li
    Zhang, Wenjia
    Wang, Xiaodong
    Dong, Wenjuan
    Tong, Yaoli
    Dong, Chuan
    Shuang, Shaomin
    ANALYST, 2019, 144 (02) : 439 - 447
  • [36] Highly Selective Two-Photon Fluorescent Probe for Ratiometric Sensing and Imaging Cysteine in Mitochondria
    Niu, Weifen
    Guo, Lei
    Li, Yinhui
    Shuang, Shaomin
    Dong, Chuan
    Wong, Man Shing
    ANALYTICAL CHEMISTRY, 2016, 88 (03) : 1908 - 1914
  • [37] A fluorescent probe emitting in near-infrared region for sensitive and selective detection of biothiols in both solution and living cells
    Chen, Wenqiang
    Luo, Hongchen
    Liu, Xingjiang
    Qi, Fengpei
    Yang, Dalei
    Song, Xiangzhi
    TETRAHEDRON LETTERS, 2015, 56 (52) : 7176 - 7179
  • [38] A novel ratiometric BenzoBODIPY-Based fluorescent probe for the detection and imaging of Cysteine in living cells and zebrafish models
    Fan, Jiaxin
    Lin, Bin
    Tang, Shuqi
    Han, Yifeng
    TALANTA, 2025, 285
  • [39] A TAT peptide-based ratiometric two-photon fluorescent probe for detecting biothiols and sequentially distinguishing GSH in mitochondria
    Su, Pingru
    Zhu, Zhanwu
    Tian, Yihong
    Liang, Lijuan
    Wu, Wenyu
    Cao, Jing
    Cheng, Bo
    Liu, Weisheng
    Tang, Yu
    TALANTA, 2020, 218
  • [40] A Two-Photon Fluorescent Probe for Lysosomal Thiols in Live Cells and Tissues
    Fan, Jiangli
    Han, Zhichao
    Kang, Yao
    Peng, Xiaojun
    SCIENTIFIC REPORTS, 2016, 6
12345