Prepregnancy obesity and the risk of birth defects: an update

被引：44

作者：

Correa, Adolfo ^{[1
,2
]}

Marcinkevage, Jessica ^{[3
]}

机构：

[1] Univ Mississippi, Med Ctr, Dept Med, Jackson, MS 39216 USA

[2] Univ Mississippi, Med Ctr, Dept Pediat, Jackson, MS 39216 USA

[3] Emory Univ, Program Nutr & Hlth Sci, Grad Div Biol & Biomed Sci, Laney Grad Sch, Atlanta, GA 30322 USA

来源：

NUTRITION REVIEWS | 2013年 / 71卷

关键词：

adverse pregnancy outcomes; birth defects; prepregnancy obesity; BODY-MASS INDEX; CONGENITAL HEART-DEFECTS; MATERNAL OBESITY; CARDIOVASCULAR-DISEASE; SCIENTIFIC STATEMENT; INFANT-MORTALITY; ASSOCIATION; ANOMALIES; WOMEN; ADIPOSITY;

D O I：

10.1111/nure.12058

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

The growing number of obese women worldwide has many implications for the reproductive health outcomes of mothers and their children. Specifically, prepregnancy obesity has been associated with certain major birth defects. Provided here is a summary of the most recent and comprehensive meta-analysis of reports of associations between prepregnancy obesity and birth defects, along with an update that includes a brief overview of reports of similar associations published since that meta-analysis. The possible reasons for the observed association between prepregnancy obesity and birth defects are explored, and knowledge gaps that suggest possible avenues for future research are highlighted. (C) 2013 International Life Sciences Institute

引用

页码：S68 / S77

页数：10

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