Silica nanoparticle remodeling under mild conditions: versatile one step conversion of mesoporous to hollow nanoparticles with simultaneous payload loading

被引：2
作者：
Shaffer, Cassandra C. C. [1 ]
Zhai, Canjia [1 ]
Chasteen, Jordan L. L. [1 ]
Orlova, Tatyana [2 ]
Zhukovskyi, Maksym [2 ]
Smith, Bradley D. D. [1 ]
机构：
[1] Univ Notre Dame, Dept Chem & Biochem, Notre Dame, IN 46556 USA
[2] Univ Notre Dame, Notre Dame Integrated Imaging Facil, Notre Dame, IN 46556 USA
来源：
NANOSCALE | 2022年 / 14卷 / 47期
关键词：
MITOXANTRONE; FUNCTIONALIZATION; POLYAMINES; DELIVERY; RELEASE; COPPER;
D O I：
10.1039/d2nr05528g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A binary mixture of mesoporous silica nanoparticles plus organic polyammonium additive (dye or drug) is cleanly converted upon mild heating into hollow nanoparticles. The remodeled nanoparticle shell is an organized nanoscale assembly of globular additive/silica subunits and cancer cell assays show that a loaded drug additive is bioavailable.
引用
收藏
页码：17514 / 17518
页数：5
相关论文
共 54 条
  • [1] An overview of the fundamentals of the chemistry of silica with relevance to biosilicification and technological advances
    Belton, David J.
    Deschaume, Olivier
    Perry, Carole C.
    [J]. FEBS JOURNAL, 2012, 279 (10) : 1710 - 1720
  • [2] Biomimetic synthesis of silica nanospheres depends on the aggregation and phase separation of polyamines in aqueous solution
    Brunner, E
    Lutz, K
    Sumper, M
    [J]. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2004, 6 (04) : 854 - 857
  • [3] Self-Assembled Surfactant-Templated Synthesis of Porous Hollow Silica Nanoparticles: Mechanism of Formation and Feasibility of Post-Synthesis Nanoencapsulation
    Bueno, Vinicius
    Ghoshal, Subhasis
    [J]. LANGMUIR, 2020, 36 (48) : 14633 - 14643
  • [4] Shortwave Infrared Imaging with J-Aggregates Stabilized in Hollow Mesoporous Silica Nanoparticles
    Chen, Wei
    Cheng, Chi-An
    Cosco, Emily D.
    Ramakrishnan, Shyam
    Lingg, Jakob G. P.
    Bruns, Oliver T.
    Zink, Jeffrey I.
    Sletten, Ellen M.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019, 141 (32) : 12475 - 12480
  • [5] Chen Y, 2019, METALS-BASEL, V9, DOI [10.3390/met9070718, 10.3390/min9100587]
  • [6] Colloidal stability and degradability of silica nanoparticles in biological fluids: a review
    da Cruz Schneid, Andressa
    Albuquerque, Lindomar Jose Calumby
    Mondo, Gabriela Borba
    Ceolin, Marcelo
    Picco, Agustin Silvio
    Cardoso, Mateus Borba
    [J]. JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 2022, 102 (01) : 41 - 62
  • [7] Della Rosa G., 2020, SCI REP-UK, V10, P1
  • [8] Mitoxantrone, More than Just Another Topoisomerase II Poison
    Evison, Benny J.
    Sleebs, Brad E.
    Watson, Keith G.
    Phillips, Don R.
    Cutts, Suzanne M.
    [J]. MEDICINAL RESEARCH REVIEWS, 2016, 36 (02) : 248 - 299
  • [9] Progress in Amine-Functionalized Silica for CO2 Capture: Important Roles of Support and Amine Structure
    Fan, Yanfang
    Jia, Xiaohao
    [J]. ENERGY & FUELS, 2022, 36 (03) : 1252 - 1270
  • [10] Mesoporous Silica Nanoparticles: Properties and Strategies for Enhancing Clinical Effect
    Frickenstein, Alex N.
    Hagood, Jordan M.
    Britten, Collin N.
    Abbott, Brandon S.
    McNally, Molly W.
    Vopat, Catherine A.
    Patterson, Eian G.
    MacCuaig, William M.
    Jain, Ajay
    Walters, Keisha B.
    McNally, Lacey R.
    [J]. PHARMACEUTICS, 2021, 13 (04)
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