Outcome of Functional Constipation in Childhood: A 10-Year Follow-Up Study

Objectives To assess the outcome of patients presenting with functional constipation in childhood during a 10-year period and to determine any risk factors for developing persistent constipation through-out adolescence and adulthood. Patients and Methods 72 children (mean age 4 years; 40 boys) referred for constipation were included in a longitudinal set of observations. Initial workup included segmental colonic transit time and anorectal manometry 45 of the 72 patients could lie reevaluated 10 to 12 years later. Results 21 of 45 patients (46%; 95% confidence interval 2996 to 6791) remained constipated at follow-up.Encopresis and recurrent MOWN pain were present in 25% and 56% of patients respectively Patients with anorectal dyssynergia remained more frequently constipated at follow-up than the others: 61% versus 29% (P <.05). Conclusion Almost 50% of, patients presenting with constipation during childhood remained constipated on long-term follow-up. Anorectal dyssynergia is associated with a wove prognosis.