Protein C and protein S deficiency presenting as Budd-Chiari syndrome

被引：3

作者：

Uvaraj, Periasamy ^{[1
]}

Rathisharmila, Ramar ^{[1
]}

Ilamaran, Veerappan ^{[1
]}

机构：

[1] Melmaruvathur Adhiparasakthi Inst Med Sci & Res, Dept Paediat, Melmaruvathur 603319, Tamil Nadu, India

来源：

BLOOD COAGULATION & FIBRINOLYSIS | 2013年 / 24卷 / 06期

关键词：

Budd-Chiari syndrome; protein C; protein S; PORTAL-VEIN THROMBOSIS; DEFECTS;

D O I：

10.1097/MBC.0b013e3283609972

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Protein C and S are vitamin K-dependent natural anticoagulants. They play a major role in hemostasis by degrading the activated factor V and factor VIII. Deficiencies of protein C and protein S are associated with increased risk of thrombotic events. The combined occurrence of protein C and S deficiency has been rarely reported. We report a 6-year-old boy with Budd-Chiari syndrome due to combined protein C and protein S deficiency. He was managed with low molecular weight heparin and discharged on long-term warfarin therapy.

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页码：652 / 654

页数：3

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