Phyllaciduloids A-D: Four new cleistanthane diterpenoids from Phyllanthus acidus (L.) Skeels

被引：17

作者：

Zheng, Xiao-Hong ^{[1
,2
]}

Yang, Jing ^{[1
,3
]}

Lv, Jun-Jiang ^{[4
]}

Zhu, Hong-Tao ^{[1
,3
]}

Wang, Dong ^{[1
,3
]}

Xu, Min ^{[5
]}

Yang, Chong-Ren ^{[1
]}

Zhang, Ying-Jun ^{[1
,3
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China

[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

[3] Chinese Acad Sci, Kunming Inst Bot, Yuman Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China

[4] Chongqing Univ, Chem & Chem Engn Coll, Chongqing 400030, Peoples R China

[5] Kunming Univ Technol & Sci, Fac Life Sci & Technol, Kunming 650504, Yunnan, Peoples R China

来源：

FITOTERAPIA | 2018年 / 125卷

基金：

中国国家自然科学基金;

关键词：

Phyllanthus acidus; Phyllanthaceae; Cleistanthane diterpenoids; Phyllaciduloids A-D; EXTRACTS; SESQUITERPENOIDS; EUPHORBIACEAE; EMBLICA; PLANTS;

D O I：

10.1016/j.fitote.2017.12.005

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Four new cleistanthane diterpenoids, phyllaciduloids A-D (1-4), were isolated from the roots and stems of Phyllanthus acidus (L.) Skeels (Phyllanthaceae). Their structures were elucidated on the basis of extensive spectroscopic analysis. Phyllaciduloids B-D (2-4) present in their structures with ether bond between C-7 and C-16, which were rarely reported. All the isolates were evaluated for their cytotoxic activities against five human cancer cell lines.

引用

页码：89 / 93

页数：5

共 50 条

[1] Phyllaciduloids E and F, two new cleistanthane diterpenoids from the leaves of Phyllanthus acidus
Geng, Hui-Chun
Zhu, Hong-Tao
Yang, Wei-Nong
Wang, Dong
Yang, Chong-Ren
Zhang, Ying-Jun
NATURAL PRODUCT RESEARCH, 2022, 36 (20) : 5241 - 5246
[2] New ent-Kaurane and cleistanthane diterpenoids with potential cytotoxicity from Phyllanthus acidus (L.) Skeels
Xin, Ying
Xu, Jia
Lv, Jun-Jiang
Zhu, Hong-Tao
Wang, Dong
Yang, Chong-Ren
Zhang, Ying-Jun
FITOTERAPIA, 2022, 157
[3] Chemical Constituents of Phyllanthus acidus (L.) Skeels
Alimboyoguen, Agnes B.
De Castro-Cruz, Kathlia A.
Fidel, Evangelina M.
Shen, Chien-Chang
Tsai, Po-Wei
INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2022, 56 (02) : 455 - 460
[4] Phyllanacidins A-C, three new cleistanthane diterpenoids from Phyllanthus acidus and their cytotoxicities
Geng, Hui-Chun
Zhu, Hong-Tao
Wang, Dong
Yang, Wei-Nong
Yang, Chong-Ren
Zhang, Ying-Jun
FITOTERAPIA, 2021, 148
[5] Four new diterpenoids from the twigs and leaves of Phyllanthus acidus
Yuan, Yu-Rong
Li, Yan-Wen
Huang, Yi-Qi
Liu, Qun-fang
Ren, Yu-Hao
Yue, Jian-Min
Zhou, Bin
TETRAHEDRON, 2021, 91
[6] Phytocompounds from Phyllanthus acidus (L.) Skeels in the management of Monkeypox Virus infections
Datta, Sutapa
Sarkar, Indrani
Goswami, Nabajyoti
Mahanta, Saurov
Borah, Probodh
Sen, Arnab
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2025, 43 (02): : 1083 - 1100
[7] The hepatoprotective activity of a new derivative kaempferol glycoside from the leaves of Vietnamese Phyllanthus acidus (L.) Skeels
Nguyen Cong Thuy Tram
Ninh The Son
Nguyen Thi Nga
Vu Thi Thu Phuong
Nguyen Thi Cuc
Do Thi Phuong
Truan, Gilles
Nguyen Manh Cuong
Do Thi Thao
MEDICINAL CHEMISTRY RESEARCH, 2017, 26 (09) : 2057 - 2064
[8] Flavonoids from the fruits of Phyllanthus acidus (L.) Skeels with anti-α-glucosidase activity
Xu, Jia
Xin, Ying
Zhu, Hong-Tao
Kong, Qing-Hua
Yang, Wei-Nong
Wang, Dong
Yang, Chong-Ren
Zhang, Ying-Jun
NATURAL PRODUCT RESEARCH, 2023, 37 (12) : 1986 - 1992
[9] Isolation and characterization of α-glucosidase inhibitors from Phyllanthus acidus (L.) Skeels stem bark
Siddiqui, Zeba
Khan, Mohammad Irfan
Badruddeen
Akhtar, Juber
Ahmad, Mohammad
Manvi
Fatima, Gayyur
ANNALS OF PHYTOMEDICINE-AN INTERNATIONAL JOURNAL, 2024, 13 (01): : 1100 - 1110
[10] The hepatoprotective activity of a new derivative kaempferol glycoside from the leaves of Vietnamese Phyllanthus acidus (L.) Skeels
Nguyen Cong Thuy Tram
Ninh The Son
Nguyen Thi Nga
Vu Thi Thu Phuong
Nguyen Thi Cuc
Do Thi Phuong
Gilles Truan
Nguyen Manh Cuong
Do Thi Thao
Medicinal Chemistry Research, 2017, 26 : 2057 - 2064

← 1 2 3 4 5 →