Pretreatment of Uterine Fibroids Using a Selective Progesterone Receptor Modulator - Ulipristal Acetate

被引：0

作者：

Thompson, M. ^{[1
,2
,3
]}

Wong, M. ^{[1
,2
,3
]}

Opemuyi, I. ^{[1
,2
,3
]}

Madipola, N. ^{[1
,2
,3
]}

Ramadan, T. ^{[4
,5
,6
]}

Nnochiri, A. ^{[1
,2
,3
]}

Guttman, J. ^{[4
,5
,6
]}

机构：

[1] Barking Univ Teaching Hosp, Dept Obstet & Gynecol, Queens Hosp Romford, London, England

[2] Havering Univ Teaching Hosp, Dept Obstet & Gynecol, Queens Hosp Romford, London, England

[3] Redbridge Univ Teaching Hosp, Dept Obstet & Gynecol, Queens Hosp Romford, London, England

[4] Barking,Univ Teaching Hosp, Dept Radiol, Queens Hosp Romford, London, England

[5] Havering Univ Teaching Hosp, Dept Radiol, Queens Hosp Romford, London, England

[6] Redbridge Univ Teaching Hosp, Dept Radiol, Queens Hosp Romford, London, England

来源：

20TH WORLD CONGRESS ON CONTROVERSIES IN OBSTETRICS, GYNECOLOGY & INFERTILITY (COGI) | 2015年

关键词：

ulipristal acetate; selective progesterone receptor modulator; uterine leiomyoma; black women; PATHOGENESIS; LEIOMYOMA; SURGERY;

D O I：

暂无

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

We report on the findings of a prospective clinical audit of the use of Ulipristal acetate for pre-treatment of symptomatic uterine fibroids in a multi-ethnic population. A total of 59 women given a 3-months treatment course of Ulipristal Acetate 5mg daily were studied. Primary outcome measures were fibroid volume reduction and amenorrhoea rates. Analysis showed that although fibroid volume reduction rates were comparable to those published in the PEARL I and II studies, amenorrhoea rates were significantly lower. Our study population has a significantly higher representation of black women which may suggest that racial differences influence selective progesterone receptor modulator treatment responses.

引用

页码：205 / 210

页数：6

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