DIALIGN at GOBICS-multiple sequence alignment using various sources of external information

被引：40

作者：

Al Ait, Layal ^{[1
]}

Yamak, Zaher ^{[2
]}

Morgenstern, Burkhard ^{[1
]}

机构：

[1] Univ Gottingen, Inst Microbiol & Genet, Dept Bioinformat, D-37077 Gottingen, Germany

[2] Ecole Doctorale Sci & Technol, Azm Ctr Res Biotechnol & Its Applicat, Bioinformat Grp, Beirut, Lebanon

来源：

NUCLEIC ACIDS RESEARCH | 2013年 / 41卷 / W1期

关键词：

PROTEIN; SERVER; DNA;

D O I：

10.1093/nar/gkt283

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

DIALIGN is an established tool for multiple sequence alignment that is particularly useful to detect local homologies in sequences with low overall similarity. In recent years, various versions of the program have been developed, some of which are fully automated, whereas others are able to accept user-specified external information. In this article, we review some versions of the program that are available through 'Gottingen Bioinformatics Compute Server'. In addition to previously described implementations, we present a new release of DIALIGN called 'DIALIGN-PFAM', which uses hits to the PFAM database for improved protein alignment. Our software is available through http://dialign.gobics.de/.

引用

页码：W3 / W7

页数：5

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