Application of Multi-component Reaction in Synthesis of Multi-substituted lmidazoles

被引：9
|
作者：
Xiao, Liwei [1 ]
Peng, Xiaoxia [1 ]
Zhou, Qiuxiang [1 ]
Kou, Wei [1 ]
Shi, Yaru [1 ]
机构：
[1] Langfang Teachers Univ, Fac Chem & Mat Sci, Langfang 065000, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 35卷 / 06期
关键词：
tri-substituted imidazoles; tetra-substituted imidazoles; multi-component reaction; heterogeneous catalysis; ONE-POT SYNTHESIS; HIGHLY SUBSTITUTED IMIDAZOLES; SOLVENT-FREE SYNTHESIS; 1,2,4,5-TETRASUBSTITUTED IMIDAZOLES; TETRASUBSTITUTED IMIDAZOLES; 2,4,5-TRISUBSTITUTED IMIDAZOLES; EFFICIENT CATALYST; TRISUBSTITUTED IMIDAZOLES; RAPID SYNTHESIS; METAL-FREE;
D O I：
10.6023/cjoc201412012
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Multi substituted imidazoles including tri- and tetra-substituted imidazoles, play important roles in the field of pharmaceutical, chemical sensing and catalysis etc. Multi-component reaction (MCR), a protocol with high atom economic and reaction selectivity, has been applied widly on the synthesis of multi-substituted imidazoles. Based on different starting materials and different methods, the recent advances in the synthesis of multi-substituted imidazols via multi-component reaction are reviewed.
引用
收藏
页码：1204 / 1215
页数：12
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