Pituitary carcinoma diagnosed on fine needle aspiration: Report of a case and review of pathogenesis

被引:13
作者
Yakoushina, Tatiana V. [1 ]
Lavi, Ehud [1 ]
Hoda, R. S. [1 ]
机构
[1] New York Presbyterian Hosp, Weill Cornell Med Coll New York, Dept Pathol & Lab Med, New York, NY USA
关键词
Fine needle aspiration; pathogenesis; pituitary adenoma; pituitary carcinoma; METASTASES; ADENOMAS;
D O I
10.4103/1742-6413.67108
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Pituitary carcinoma (PC) is a very rare entity (0.2% of all pituitary tumors), with only about 140 cases reported in English literature. There are no reliable histological, immunohistochemical or ultrastructural features distinguishing pituitary adenoma (PA) from PC. By definition, a diagnosis of PC is made after a patient with PA develops non-contiguous central nervous system (CNS) or systemic metastases. To date, only three cases of PC have been reportedly diagnosed on fine needle aspiration (FNA). Two of the reported cases were diagnosed on FNA of the cervical lymph nodes and one on FNA of the vertebral bone lesion. Herein, we present a case of PC, diagnosed on FNA of the liver lesion. In this case, we describe cytologic features of PC and compare them to histologic features of the tumor in the pituitary. Clinical behavior of tumor, pathogenesis of metastasis and immunochemical and prognostic markers will also be described.
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页数:6
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