FDG-PET for detecting local tumor recurrence of ablated liver metastases: a diagnostic meta-analysis

被引:10
作者
Poulou, Loukia S. [1 ]
Ziakas, Panayiotis D. [2 ]
Ziogas, Dimitrios C. [2 ]
Doxani, Chrysoula [3 ]
Xyla, Vassilia [2 ]
Vakrinos, George [1 ]
Voulgarelis, Michael [2 ]
Thanos, Loukas [1 ]
机构
[1] Gen Hosp Chest Dis Sotiria, Dept Med Imaging & Intervent Radiol, Athens 11527, Greece
[2] Univ Athens, Sch Med, Dept Pathophysiol, Athens 11528, Greece
[3] Univ Thessaly, Sch Med, Dept Biomath, Larisa, Greece
关键词
Radiofrequency ablation; positron emission tomography; metastasis; meta-analysis; POSITRON-EMISSION-TOMOGRAPHY; RADIOFREQUENCY THERMAL ABLATION; COLORECTAL-CANCER; HEPATIC-TUMORS; FOLLOW-UP; CT; MANAGEMENT; TISSUE; PERFORMANCE; CARCINOMA;
D O I
10.3109/1354750X.2012.699553
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Context: Scanty reports have focused on FDG-PET after radiofrequency ablation (RFA), for recurrence of hepatic metastases. Objective: To assess FDG-PET diagnostic accuracy on detection of recurrent hepatic lesions. Methods: After a comprehensive search of PubMed and EMBASE, we performed a patient-based diagnostic meta-analysis of post-RFA FDG-PET. Results: Across nine included articles, independent, random-effects sensitivity and specificity were 0.73(0.50-0.88) and 0.85(0.72-0.93), respectively. A symmetrical SROC curve was produced with no significant heterogeneity. Specificity was optimal for surgical RFA and colorectal origin of metastases. Conclusion: Synthesis of published evidence suggests PET/CT as an appropriate tool for optimizing post-ablation follow-up.
引用
收藏
页码:532 / 538
页数:7
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