Glycodendrimer synthesis without using protecting groups

被引：60

作者：

Kieburg, C ^{[1
]}

Lindhorst, TK ^{[1
]}

机构：

[1] UNIV HAMBURG,DEPT ORGAN CHEM,D-20146 HAMBURG,GERMANY

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(97)00760-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oligoantennary neoglycoconjugates can act as powerful inhibitors of carbohydrate-protein interactions and thus serve as antiadhesives in carbohydrate-based adhesion systems. They were obtained by a procedure that doesn't require protecting groups. Various unprotected NCS-functionalized saccharides were coupled with oligoamines in aqueous solution. This versatile method is generally applicable to the synthesis of thiourea-bridged glycodendrimers. (C) 1997 Elsevier Science Ltd.

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页码：3885 / 3888

页数：4

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