Lipids of hamster cheek pouch epithelium

被引：2

作者：

Whittle, S ^{[1
]}

Swartzendruber, DC ^{[1
]}

Kremer, M ^{[1
]}

Squier, CA ^{[1
]}

Wertz, PW ^{[1
]}

机构：

[1] UNIV IOWA,DOWS INST,N450 DSB,IOWA CITY,IA 52242

来源：

LIPIDS | 1997年 / 32卷 / 09期

关键词：

D O I：

10.1007/s11745-997-0124-y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The hamster cheek pouch is a much used bur incompletely understood experimental model. In particular, the cheek pouch epithelial lipids, which are important for permeability barrier function as well as other aspects of epithelial biology, have not been completely characterized. In the present study, the complete lipid class composition has been determined by thin-layer chromatography in conjunction with photodensitometry. The major lipid classes were phospholipids, free sterols, and ceramides. Minor amounts of monohexosylceramides, sterol esters, fatty acids, and triglycerides were also present. Significant amounts of covalently bound omega-hydroxyceramide was also detected. Transmission electron micrographs reveal extensive, largely paired, lipid bilayers in the intercellular spaces of the stratum corneum.

引用

页码：961 / 964

页数：4

共 19 条

[1] ANIMAL-MODELS OF ORAL CANDIDIASIS - A REVIEW [J].