The role of calcium, lipid membranes and islet amyloid polypeptide in the onset of type 2 diabetes: innocent bystanders or partners in a crime?

被引：17
作者：
Milardi, Danilo [1 ]
Sciacca, Michele F. M. [2 ]
Randazzo, Loredana [1 ]
Raudino, Antonino [2 ]
La Rosa, Carmelo [2 ]
机构：
[1] Ist CNR Biostrutture & Bioimmagini, Sez Catania, Catania, Italy
[2] Univ Catania, Dipartimento Sci Chim, Viale Andrea Doria 6, Catania, Italy
来源：
FRONTIERS IN ENDOCRINOLOGY | 2014年 / 5卷
关键词：
type II diabetes mellitus; amyloid; membranes; calcium; obesity; free fatty acids; genetic predisposition; FREE FATTY-ACID; INSULIN-RESISTANCE; A-BETA; PATHOGENESIS; AGGREGATION; GLUCOSE; PROTEIN; OBESITY; AMYLIN; DISRUPTION;
D O I：
10.3389/fendo.2014.00216
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页数：4
相关论文
共 52 条
[1]   Genetics of Type 2 Diabetes [J].
Ahlqvist, Emma ;
Ahluwalia, Tarunveer Singh ;
Groop, Leif .
CLINICAL CHEMISTRY, 2011, 57 (02) :241-254
[2]   Tetracycline Treatment Retards the Onset and Slows the Progression of Diabetes in Human Amylin/Islet Amyloid Polypeptide Transgenic Mice [J].
Aitken, Jacqueline F. ;
Loomes, Kerry M. ;
Scott, David W. ;
Reddy, Shivanand ;
Phillips, Anthony R. J. ;
Prijic, Gordana ;
Fernando, Chathurini ;
Zhang, Shaoping ;
Broadhurst, Ric ;
L'Huillier, Phil ;
Cooper, Garth J. S. .
DIABETES, 2010, 59 (01) :161-171
[3]   Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes [J].
Anguiano, M ;
Nowak, RJ ;
Lansbury, PT .
BIOCHEMISTRY, 2002, 41 (38) :11338-11343
[4]   The role of low-fat diets in body weight control:: a meta-analysis of ad libitum dietary intervention studies [J].
Astrup, A ;
Grunwald, GK ;
Melanson, EL ;
Saris, WHM ;
Hill, JO .
INTERNATIONAL JOURNAL OF OBESITY, 2000, 24 (12) :1545-1552
[5]   The role of calcium in energy balance and obesity: the search for mechanisms [J].
Astrup, Arne .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2008, 88 (04) :873-874
[6]   Cellular ions in NIDDM: Relation of calcium to hyperglycemia and cardiac mass [J].
Barbagallo, M ;
Gupta, RK ;
Resnick, LM .
DIABETES CARE, 1996, 19 (12) :1393-1398
[7]   Relationship between Insulin-Like Growth Factor I Levels, Early Insulin Treatment, and Clinical Outcomes of Very Low Birth Weight Infants [J].
Beardsall, Kathryn ;
Vanhaesebrouck, Sophie ;
Frystyk, Jan ;
Ogilvy-Stuart, Amanda L. ;
Vanhole, Christine ;
van Weissenbruch, Mirjam ;
Midgley, Paula ;
Thio, Marta ;
Cornette, Luc ;
Gill, Bryan ;
Ossuetta, Iviano ;
Iglesias, Isabel ;
Theyskens, Claire ;
de Jong, Miranda ;
Ahluwalia, Jag S. ;
de Zegher, Francis ;
Dunger, David B. .
JOURNAL OF PEDIATRICS, 2014, 164 (05) :1038-+
[8]  
BJORNTORP P, 1969, ACTA MED SCAND, V185, P351
[9]   MECHANISMS OF FATTY ACID-INDUCED INHIBITION OF GLUCOSE-UPTAKE [J].
BODEN, G ;
CHEN, XH ;
RUIZ, J ;
WHITE, JV ;
ROSSETTI, L .
JOURNAL OF CLINICAL INVESTIGATION, 1994, 93 (06) :2438-2446
[10]   Role of fatty acids in the pathogenesis of insulin resistance and NIDDM [J].
Boden, G .
DIABETES, 1997, 46 (01) :3-10
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