ICCS/ESCCA consensus guidelines to detect GPI-deficient cells in paroxysmal nocturnal hemoglobinuria (PNH) and related disorders part 3-data analysis, reporting and case studies

被引：49

作者：

Illingworth, Andrea ^{[1
]}

Marinov, Iuri ^{[2
]}

Sutherland, D. Robert ^{[3
]}

Wagner-Ballon, Orianne ^{[4
]}

DelVecchio, Luigi ^{[5
,6
]}

机构：

[1] Dahl Chase Diagnost Serv Bangor, 417 State St,Suite 540, Bangor, ME 04401 USA

[2] Inst Hematol & Blood Transfus, Prague, Czech Republic

[3] Toronto Gen Hosp, Lab Med Program, Toronto, ON, Canada

[4] Hop Henri Mondor, Dept Hematol & Immunol Biol, Creteil, France

[5] Univ Naples Federico II, Naples, Italy

[6] CEINGE Inst Naples, Naples, Italy

来源：

CYTOMETRY PART B-CLINICAL CYTOMETRY | 2018年 / 94卷 / 01期

关键词：

PNH; paroxysmal; nocturnal; hemoglobinuria; flow cytometry; monocytes; neutrophils; PERIPHERAL-BLOOD CELLS; FLOW-CYTOMETRY; APLASTIC-ANEMIA; NATURAL-HISTORY; DIAGNOSIS; MANAGEMENT; SUBSETS; ASSAYS; CD157;

D O I：

10.1002/cyto.b.21609

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Over the past several years, a diverse group of physicians and other laboratory scientists have developed various recommendations and guidelines regarding best practices for PNH testing. This manuscript is based on these previous recommendations as well as various other relevant publications of experts in the area of PNH testing. The goal is to provide flow cytometry laboratories with an updated consensus approach to analysis and reporting of PNH results and to address the most common analytical challenges for accurate reporting of this rare disease. A comprehensive case library is included in this section. (c) 2017 International Clinical Cytometry Society

引用

页码：49 / 66

页数：18

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