Synthesis of lipophilic N-phosphorylmethylated amino acids and their membrane-transport properties towards some organic acids

被引：1
作者：
Cherkasov, Rafael A. [1 ]
Koshkin, Sergey A. [1 ]
Garifzyanov, Airat R. [1 ]
Davletshina, Natal'ya V. [1 ]
机构：
[1] Kazan Volga Reg Fed Univ, AM Butlerov Chem Res Inst, Kazan, Russia
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2016年 / 191卷 / 11-12期
关键词：
Amino acids; membrane transport; synthesis;
D O I：
10.1080/10426507.2016.1223666
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
One-pot procedures were developed for the synthesis of lipophilic N-(dialkylphosphorylmethyl) derivatives of natural amino acids with high yields from dioctyloxide, formaldehyde, and an amino acid in the presence of amino acid hydrochloride. Membrane transport properties of the new phosphorylated amino acids towards polyfunctional carboxylic acids were studied. It was found that N,N-bis[(dioctylphosphoryl)methyl]--alanine is a selective extractant for glutaric acid. [GRAPHICS] .
引用
收藏
页码：1650 / 1651
页数：2
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