Computational Genomics of noncoding RNA genes

被引：184

作者：

Eddy, SR ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Howard Hughes Med Inst, Dept Genet, St Louis, MO 63110 USA

来源：

CELL | 2002年 / 109卷 / 02期

关键词：

D O I：

10.1016/S0092-8674(02)00727-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The number of known noncoding RNA genes is expanding rapidly. Computational analysis of genome sequences, which has been revolutionary for protein gene analysis, should also be able to address questions of the number and diversity of noncoding RNA genes. However, noncoding RNAs present computational genomics with a new set of challenges.

引用

页码：137 / 140

页数：4

共 18 条

[1] AMINO-ACID SUBSTITUTION MATRICES FROM AN INFORMATION THEORETIC PERSPECTIVE
ALTSCHUL, SF
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1991, 219 (03) : 555 - 565
[2] microRNAs: Tiny regulators with great potential
Ambros, V
[J]. CELL, 2001, 107 (07) : 823 - 826
[3] Novel small RNA-encoding genes in the intergenic regions of Escherichia coli
Argaman, L
Hershberg, R
Vogel, J
Bejerano, G
Wagner, EGH
Margalit, H
Altuvia, S
[J]. CURRENT BIOLOGY, 2001, 11 (12) : 941 - 950
[4] Atkins J. F., 1999, RNA WORLD
[5] A computational approach to identify genes for functional RNAs in genomic sequences
Carter, RJ
Dubchak, I
Holbrook, SR
[J]. NUCLEIC ACIDS RESEARCH, 2001, 29 (19) : 3928 - 3938
[6] FINDING THE HAIRPIN IN THE HAYSTACK - SEARCHING FOR RNA MOTIFS
DANDEKAR, T
HENTZE, MW
[J]. TRENDS IN GENETICS, 1995, 11 (02) : 45 - 50
[7] Durbin R., 1998, BIOL SEQUENCE ANAL P
[8] Non-coding RNA genes and the modern RNA world
Eddy, SR
[J]. NATURE REVIEWS GENETICS, 2001, 2 (12) : 919 - 929
[9] Small nucleolar RNAs
Eliceiri, GL
[J]. CELLULAR AND MOLECULAR LIFE SCIENCES, 1999, 56 (1-2) : 22 - 31
[10] The non-coding RNAs as riboregulators
Erdmann, VA
Barciszewska, MZ
Szymanski, M
Hochberg, A
de Groot, N
Barciszewski, J
[J]. NUCLEIC ACIDS RESEARCH, 2001, 29 (01) : 189 - 193

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