Environmental and Genetic Risk Factors in Obesity

被引：87
作者：
Hebebrand, Johannes [1 ]
Hinney, Anke [1 ]
机构：
[1] Univ Duisburg Essen, Rhein Kliniken Essen, Dept Child & Adolescent Psychiat, D-45147 Essen, Germany
来源：
CHILD AND ADOLESCENT PSYCHIATRIC CLINICS OF NORTH AMERICA | 2009年 / 18卷 / 01期
关键词：
Monogenic; Polygenic; Socioeconomic status; Television; BODY-MASS INDEX; GENOME-WIDE ASSOCIATION; CHILDHOOD OBESITY; PHYSICAL-ACTIVITY; SOCIOECONOMIC-STATUS; ENERGY-EXPENDITURE; SOCIAL-CLASS; FAT MASS; CHILDREN; WEIGHT;
D O I：
10.1016/j.chc.2008.07.006
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Because of its high prevalence and the associated medical and psychosocial risks, research into the causes of childhood obesity has experienced a tremendous upswing. Formal genetic data based on twin, adoption, and family studies lead to the conclusion that at least 50% of the interindividual variance of the body mass index (BMI; defined as weight in kilograms divided by height in meters squared) is due to genetic factors. As a result of the recent advent of genome-wide association studies, the first
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页码：83 / +
页数：14
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