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Environmental and Genetic Risk Factors in Obesity
被引:87
作者:
Hebebrand, Johannes
[1
]
Hinney, Anke
[1
]
机构:
[1] Univ Duisburg Essen, Rhein Kliniken Essen, Dept Child & Adolescent Psychiat, D-45147 Essen, Germany
关键词:
Monogenic;
Polygenic;
Socioeconomic status;
Television;
BODY-MASS INDEX;
GENOME-WIDE ASSOCIATION;
CHILDHOOD OBESITY;
PHYSICAL-ACTIVITY;
SOCIOECONOMIC-STATUS;
ENERGY-EXPENDITURE;
SOCIAL-CLASS;
FAT MASS;
CHILDREN;
WEIGHT;
D O I:
10.1016/j.chc.2008.07.006
中图分类号:
R749 [精神病学];
学科分类号:
100205 ;
摘要:
Because of its high prevalence and the associated medical and psychosocial risks, research into the causes of childhood obesity has experienced a tremendous upswing. Formal genetic data based on twin, adoption, and family studies lead to the conclusion that at least 50% of the interindividual variance of the body mass index (BMI; defined as weight in kilograms divided by height in meters squared) is due to genetic factors. As a result of the recent advent of genome-wide association studies, the first
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页码:83 / +
页数:14
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