Sc(OTf)3-catalyzed smooth tandem [3+2] cycloaddition/ring opening of donor-acceptor cyclopropane 1,1-diesters with enol silyl ethers

被引：61

作者：

Fang, Jie ^{[1
]}

Ren, Jun ^{[1
]}

Wang, Zhongwen ^{[1
]}

机构：

[1] Nankai Univ, Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 30071, Peoples R China

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 47期

基金：

中国国家自然科学基金;

关键词：

Tandem; Cyclopropane; Cycloaddition; Enol silyl ether; Ring opening;

D O I：

10.1016/j.tetlet.2008.09.028

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Catalyzed by Lewis acids, donor-acceptor cyclopropane 1,1-diesters reacted with enol silyl ethers to afford 1,6-dicarbonyl compounds in moderate to excellent yields. This supplied a mild carbon-carbon bond-forming method from the ring opening of cyclopropanes. A smooth tandem [3+2] cycloaddition/ring opening process has been clearly proved by an independent experiment. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：6659 / 6662

页数：4

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