Cell Therapy Needs Rigorous Translational Studies in Large Animal Models

被引:25
作者
Bolli, Roberto [1 ]
Ghafghazi, Shahab [1 ]
机构
[1] Univ Louisville, Div Cardiol, Dept Med, Inst Mol Cardiol, Louisville, KY 40202 USA
关键词
cardiac stem cells; cell therapy; congestive heart failure; ischemic cardiomyopathy; large animal models; mesenchymal stem cells; CARDIAC STEM-CELLS; MYOCARDIAL-INFARCTION; SKELETAL MYOBLASTS; COMBINED TRANSPLANTATION; ISCHEMIC CARDIOMYOPATHY; PROGENITOR CELLS; HEART-FAILURE; REPAIR; PARADIGM; IMPROVES;
D O I
10.1016/j.jacc.2015.09.002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2000 / 2004
页数:5
相关论文
共 19 条
[1]   Combined Intramyocardial Delivery of Human Pericytes and Cardiac Stem Cells Additively Improves the Healing of Mouse Infarcted Hearts Through Stimulation of Vascular and Muscular Repair [J].
Avolio, Elisa ;
Meloni, Marco ;
Spencer, Helen L. ;
Riu, Federica ;
Katare, Rajesh ;
Mangialardi, Giuseppe ;
Oikawa, Atsuhiko ;
Rodriguez-Arabaolaza, Iker ;
Dang, Zexu ;
Mitchell, Kathryn ;
Reni, Carlotta ;
Alvino, Valeria V. ;
Rowlinson, Jonathan ;
Livi, Ugolini ;
Cesselli, Daniela ;
Angelini, Gianni ;
Emanueli, Costanza ;
Beltrami, Antonio P. ;
Madeddu, Paolo .
CIRCULATION RESEARCH, 2015, 116 (10) :E81-E94
[2]   RETRACTED: Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial (Retracted article. See vol. 393, pg. 1084, 2019) [J].
Bolli, Roberto ;
Chugh, Atul R. ;
D'Amario, Domenico ;
Loughran, John H. ;
Stoddard, Marcus F. ;
Ikram, Sohail ;
Beache, Garth M. ;
Wagner, Stephen G. ;
Leri, Annarosa ;
Hosoda, Toru ;
Sanada, Fumihiro ;
Elmore, Julius B. ;
Goichberg, Polina ;
Cappetta, Donato ;
Solankhi, Naresh K. ;
Fahsah, Ibrahim ;
Rokosh, D. Gregg ;
Slaughter, Mark S. ;
Kajstura, Jan ;
Anversa, Piero .
LANCET, 2011, 378 (9806) :1847-1857
[3]  
Bonaros Nikolaos, 2008, Interact Cardiovasc Thorac Surg, V7, P249
[4]   Combined transplantation of skeletal myoblasts and angiopoietic progenitor cells reduces infarct size and apoptosis and improves cardiac function in chronic ischemic heart failure [J].
Bonaros, Nikolaos ;
Rauf, Rauend ;
Wolf, Dominik ;
Margreiter, Eva ;
Tzankov, Alexandar ;
Schlechta, Bernhard ;
Kocher, Alfred ;
Ott, Harald ;
Schachner, Thomas ;
Hering, Steffen ;
Bonatti, Johannes ;
Laufer, Guenther .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2006, 132 (06) :1321-U13
[5]   Safety and Efficacy of Ixmyelocel-T An Expanded, Autologous Multi-Cellular Therapy, in Dilated Cardiomyopathy [J].
Henry, Timothy D. ;
Traverse, Jay H. ;
Hammon, Baron L. ;
East, Cara A. ;
Bruckner, Brian ;
Remmers, Ann E. ;
Recker, David ;
Bull, David A. ;
Patel, Amit N. .
CIRCULATION RESEARCH, 2014, 115 (08) :730-+
[6]   The NHLBI-Sponsored Consortium for preclinicAl assESsment of cARdioprotective Therapies (CAESAR) A New Paradigm for Rigorous, Accurate, and Reproducible Evaluation of Putative Infarct-Sparing Interventions in Mice, Rabbits, and Pigs [J].
Jones, Steven P. ;
Tang, Xian-Liang ;
Guo, Yiru ;
Steenbergen, Charles ;
Lefer, David J. ;
Kukreja, Rakesh C. ;
Kong, Maiying ;
Li, Qianhong ;
Bhushan, Shashi ;
Zhu, Xiaoping ;
Du, Junjie ;
Nong, Yibing ;
Stowers, Heather L. ;
Kondo, Kazuhisa ;
Hunt, Gregory N. ;
Goodchild, Traci T. ;
Orr, Adam ;
Chang, Carlos C. ;
Ockaili, Ramzi ;
Salloum, Fadi N. ;
Bolli, Roberto .
CIRCULATION RESEARCH, 2015, 116 (04) :572-586
[7]   Synergistic Effects of Combined Cell Therapy for Chronic Ischemic Cardiomyopathy [J].
Karantalis, Vasileios ;
Suncion-Loescher, Viky Y. ;
Bagno, Luiza ;
Golpanian, Samuel ;
Wolf, Ariel ;
Sanina, Cristina ;
Premer, Courtney ;
Kanelidis, Anthony J. ;
McCall, Frederic ;
Wang, Bo ;
Balkan, Wayne ;
Rodriguez, Jose ;
Rosado, Marcos ;
Morales, Azorides ;
Hatzistergos, Konstantinos ;
Natsumeda, Makoto ;
Margitich, Irene ;
Schulman, Ivonne Hernandez ;
Gomes, Samirah A. ;
Mushtaq, Muzammil ;
DiFede, Darcy L. ;
Fishman, Joel E. ;
Pattany, Pradip ;
Zambrano, Juan Pablo ;
Heldman, Alan W. ;
Hare, Joshua M. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2015, 66 (18) :1990-1999
[8]   Use of Mesenchymal Stem Cells for Therapy of Cardiac Disease [J].
Karantalis, Vasileios ;
Hare, Joshua M. .
CIRCULATION RESEARCH, 2015, 116 (08) :1413-1430
[9]   "String Theory" of c-kitpos Cardiac Cells A New Paradigm Regarding the Nature of These Cells That May Reconcile Apparently Discrepant Results [J].
Keith, Matthew C. L. ;
Bolli, Roberto .
CIRCULATION RESEARCH, 2015, 116 (07) :1216-1230
[10]   Human Blood and Cardiac Stem Cells Synergize to Enhance Cardiac Repair When Cotransplanted Into Ischemic Myocardium [J].
Latham, Nicholas ;
Ye, Bin ;
Jackson, Robyn ;
Lam, Bu-Khanh ;
Kuraitis, Drew ;
Ruel, Marc ;
Suuronen, Erik J. ;
Stewart, Duncan J. ;
Davis, Darryl R. .
CIRCULATION, 2013, 128 (11) :S105-S112