African Swine Fever Virus Isolate, Georgia, 2007

被引:420
作者
Rowlands, Rebecca J.
Michaud, Vincent [2 ]
Heath, Livio [3 ]
Hutchings, Geoff
Oura, Chris
Vosloo, Wilna [3 ,4 ]
Dwarka, Rahana [3 ]
Onashvili, Tinatin [5 ]
Albina, Emmanuel [2 ]
Dixon, Linda K. [1 ]
机构
[1] Inst Anim Hlth, Pirbright Lab, Surrey GU24 ONF, England
[2] Ctr Cooperat Int Rech Agron Dev, Montpellier, France
[3] Agr Res Council Onderstepoort Vet Inst, Onderstepoort, South Africa
[4] Univ Pretoria, ZA-0002 Pretoria, South Africa
[5] Lab Minist Agr Georgia, Tbilisi, Georgia
基金
英国惠康基金; 英国生物技术与生命科学研究理事会;
关键词
D O I
10.3201/eid1412.080591
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
African swine fever (ASF) is widespread in Africa but is rarely introduced to other continents. In June 2007, ASF was confirmed in the Caucasus region of Georgia, and it has since spread to neighboring countries. DNA fragments amplified from the genome of the isolates from domestic pigs in Georgia in 2007 were sequenced and compared with other ASF virus (ASFV) isolates to establish the genotype of the virus. Sequences were obtained from 4 genome regions, including part of the gene B646L that encodes the p72 capsid protein, the complete E183L and CP204L genes, which encode the p54 and p30 proteins and the variable region of the B602L gene. Analysis of these sequences indicated that the Georgia 2007 isolate is closely related to isolates belonging to genotype 11, which is circulating in Mozambique, Madagascar, and Zambia. One possibility for the spread of disease to Georgia is that pigs were fed ASFVcontaminated pork brought in on ships and, subsequently, the disease was disseminated throughout the region.
引用
收藏
页码:1870 / 1874
页数:5
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