Seaweed Phenolics: From Extraction to Applications

被引：315

作者：

Cotas, Joao ^{[1
]}

Leandro, Adriana ^{[1
]}

Monteiro, Pedro ^{[2
,3
]}

Pacheco, Diana ^{[1
]}

Figueirinha, Artur ^{[2
,4
]}

Goncalves, Ana M. M. ^{[1
,5
,6
]}

da Silva, Gabriela Jorge ^{[2
,3
]}

Pereira, Leonel ^{[1
]}

机构：

[1] Univ Coimbra, MARE Marine & Environm Sci Ctr, Dept Life Sci, P-3001456 Coimbra, Portugal

[2] Univ Coimbra, Fac Pharm, Hlth Sci Campus, P-3000548 Coimbra, Portugal

[3] Univ Coimbra, Ctr Neurosci & Cell Biol, Hlth Sci Campus, P-3000548 Coimbra, Portugal

[4] Univ Coimbra, LAQV, REQUIMTE, Fac Pharm, P-3000548 Coimbra, Portugal

[5] Univ Aveiro, Dept Biol, P-3810193 Aveiro, Portugal

[6] Univ Aveiro, CESAM, P-3810193 Aveiro, Portugal

来源：

MARINE DRUGS | 2020年 / 18卷 / 08期

关键词：

seaweed polyphenolics; polyphenolics extractions; phlorotannins; bromophenols; flavonoids; phenolic terpenoids; polyphenolics bioactivities; EDIBLE BROWN ALGA; VITRO ANTIVIRAL ACTIVITY; BROMOPHENOL BIS(2,3-DIBROMO-4,5-DIHYDROXYBENZYL) ETHER; ALLEVIATES POSTPRANDIAL HYPERGLYCEMIA; POTENT ALPHA-GLUCOSIDASE; ESCHERICHIA-COLI O157-H7; TYROSINE-PHOSPHATASE; 1B; V79-4 LUNG FIBROBLAST; ECKLONIA-CAVA; RED ALGA;

D O I：

10.3390/md18080384

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Seaweeds have attracted high interest in recent years due to their chemical and bioactive properties to find new molecules with valuable applications for humankind. Phenolic compounds are the group of metabolites with the most structural variation and the highest content in seaweeds. The most researched seaweed polyphenol class is the phlorotannins, which are specifically synthesized by brown seaweeds, but there are other polyphenolic compounds, such as bromophenols, flavonoids, phenolic terpenoids, and mycosporine-like amino acids. The compounds already discovered and characterized demonstrate a full range of bioactivities and potential future applications in various industrial sectors. This review focuses on the extraction, purification, and future applications of seaweed phenolic compounds based on the bioactive properties described in the literature. It also intends to provide a comprehensive insight into the phenolic compounds in seaweed.

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