Lacrimal Gland Sparing IgG4-Related Disease in the Orbit

被引:7
|
作者
Khan, Tanya T. [1 ]
Halat, Shams K. [2 ]
Al Hariri, Adham B. [3 ]
机构
[1] Ochsner Clin Fdn, Dept Ophthalmol, New Orleans, LA USA
[2] Ochsner Clin Fdn, Dept Pathol, New Orleans, LA USA
[3] Ochsner Clin Fdn, Dept Ophthalmol Oculoplast & Reconstruct Surg, New Orleans, LA USA
关键词
IgG4; lacrimal gland; orbit; ptosis; proptosis; MALT; PATHOLOGY;
D O I
10.3109/09273948.2012.762981
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: We report an unusual case of orbital IgG4-related disease and discuss the distinguishing characteristics of the ophthalmic disease subtype. Design: Case report. Methods: Literature review and case description. Results: Although lacrimal gland involvement has always been reported and elevated serum IgG4 is commonly observed, our case demonstrated neither in light of biopsy-proven IgG4 orbital involvement. A course of systemic steroids resolved our patient's periorbital abnormalities. Conclusions: IgG4-related orbital disease mandates a high index of suspicion, and should be confirmed by tissue biopsy. Possible progression to MALT lymphoma necessitates close surveillance and may require repeat biopsy.
引用
收藏
页码:220 / 224
页数:5
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