A rising interest in animal protein consumption produced from chickens in North Maluku has stimulated the development of broiler chicken farms across the region. However, broiler chicken farmers have been facing a big challenge in developing their small businesses due to costly production factors. The present study aimed at observing whether or not factors that influence the production of broiler chicken. An investigation was conducted at a Broiler Chickens Farming System developed by the RegionalTechnical Implementation Unit for Agribusiness and Livestock in Ternate from July to September 2018. The reason for selecting this area as the study site was that the chicken farm has utilized modern technology in developing this business and the farm has produced its own chicken feed. An Interview was conducted to collect data. The production factors observed consisted of the use of day-old chicken (DOC), area of the chicken house, chicken feed, antibiotic, labor, and operational cost. The data were then analyzed using a multiple linear regression model. The findings revealed that from all production factors, DOC, area of the chicken house, chicken feed and operational cost had significant effects on chicken production, while the other two factors (antibiotics and labor) had no significant effects on the production.