Morbidity and mortality of the Hartmann procedure for diverticular disease over 18 years in a single institution

被引:29
作者
Ince, M. [1 ]
Stocchi, L. [1 ]
Khomvilai, S. [1 ]
Kwon, D. S. [1 ]
Hammel, J. P. [1 ]
Kiran, R. P. [1 ]
机构
[1] Cleveland Clin Fdn, Dept Colorectal Surg, Inst Digest Dis, Cleveland, OH 44195 USA
关键词
Hartmann's procedure; perforated diverticulitis; peritonitis; LAPAROSCOPIC PERITONEAL-LAVAGE; INTRAOPERATIVE COLONIC LAVAGE; PRIMARY ANASTOMOSIS; PERFORATED DIVERTICULITIS; COMPLICATED DIVERTICULITIS; GENERALIZED PERITONITIS; SIGMOID RESECTION; SURGICAL-TREATMENT; EMERGENCY-SURGERY; UNITED-STATES;
D O I
10.1111/j.1463-1318.2012.03004.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Aim Hartmanns procedure for perforated diverticulitis is associated with substantial morbidity and mortality. This study analyses factors associated with morbidity/mortality and possible changes over time. Method Patients treated by urgent Hartmanns procedure for perforated diverticulitis between 1992 and 2010 were studied, and information was collected on age, sex, perioperative details, 30-day morbidity and mortality recorded in an institutional review board approved database supplemented by chart review. Patients were divided into four groups based on the year of surgery. Univariate and multivariate logistic regression analysis was performed to identify risk factors associated with morbidity and mortality. Results In all, 199 patients (51% female, mean age 65 years, mean body mass index 28 kg/m2) were identified. The American Society of Anesthesiologists (ASA) score was 4 in 30% of patients and Hinchey Stage IV in 16%. The mean length of stay was 12.5 +/- 10 days. Mortality was 15% and did not change significantly over time. Overall morbidity was 52% and significantly increased over time on univariate analysis (P = 0.007) but not on multivariate analysis (P = 0.11). Independent predictors of morbidity on multivariate analysis were Hinchey IV (P < 0.001) and hypoproteinaemia (P =0.001). Independent predictors for mortality were ASA > 3 (P = 0.01), abnormal creatinine (P = 0.007), steroid use (P = 0.007), Hinchey IV (P = 0.032), low albumin (P < 0.001) and low body mass index (P = 0.001). Conclusion Mortality after Hartmanns procedure for perforated diverticulitis has not decreased during the last 18 years. Morbidity has actually increased over time although this is related to increased disease severity and comorbidity. Future efforts should focus on the identification of patient subgroups benefiting from earlier elective surgery and alternative surgical approaches when perforated diverticulitis does occur.
引用
收藏
页码:E492 / E498
页数:7
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