Incidence of congenital hypothyroidism in the city of Uberaba/Minas Gerais and etiological evaluation of the affected subjects

被引：0

作者：

da Cunha Palhares, Heloisa Marcelina ^{[1
]}

Silva, Lilian Carla ^{[1
]}

Sato, Luciene Mayumi ^{[1
]}

Jorge Lara, Beatriz Hallal ^{[1
]}

Castro Miranzi, Sybele de Souza ^{[1
]}

Silva, Adriana de Paula ^{[1
]}

Borges, Maria de Fatima ^{[1
]}

机构：

[1] Univ Fed Triangulo Mineiro, Hosp Clin, Dept Clin Med, Disciplina Endocrinol, BR-38025440 Uberaba, MG, Brazil

来源：

ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA | 2012年 / 56卷 / 05期

关键词：

Congenital hypothyroidism; newborn screening; epidemiology; NEONATAL SCREENING-PROGRAM; DIAGNOSIS;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective: The objective of this study was to determine the incidence and etiology of congenital hypothyroidism (CH) in Uberaba, MG. Subjects and methods: From 2001 to 2010, by reviewing patient files from a public reference outpatient unit. The screening program covered 88% of live-born children. Results: CH was diagnosed in 16 children, representing an incidence of 1:2,017 live-born children screened. The etiological evaluation was done in 15 children and revealed seven cases of thyroid dysgenesis, seven of dyshormonogenesis, and one case of transient hypothyroidism. One child moved away from the state before etiological investigation was carried out. Conclusion: We concluded that both the incidence of CH and of dyshormonogenesis as the main causes of CH were increased in the investigated region, but molecular studies are necessary for a better definition of etiology. Arq Bras Endocrinol Metab. 2012;56(5):305-12

引用

页码：305 / 312

页数：8

共 36 条

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