Atomic force microscopy visualization of the DNA network and molecular morphological transition on a mica surface

被引:6
作者
Zhao, Feng [1 ]
Xu, Jingkun [1 ]
Liu, Shufeng [2 ]
机构
[1] Jiangxi Sci & Technol Normal Univ, Jiangxi Key Lab Organ Chem, Nanchang 330013, Peoples R China
[2] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China
关键词
DNA network; morphological transition; surface; atomic force microscopy;
D O I
10.1016/j.tsf.2008.05.030
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
In this paper, a uniform calf thymus deoxyribonucleic acid (DNA) network has been constructed on a bare mica surface using a simple adsorption method. The effect of the immersion time in water on the characteristics of the morphological transitions of DNA molecules adsorbed on the mica surface was investigated by atomic force microscopy. It was found that the DNA molecules underwent conformational transitions from stretched wormlike coil to rod and to network by changing the immersion time in water and the formation mechanism was explained briefly. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码:7555 / 7559
页数:5
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