Smoking as a Risk Factor for Complications in Chronic Pancreatitis
被引:44
作者:
Luaces-Regueira, Maria
论文数: 0引用数: 0
h-index: 0
机构:
Univ Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, SpainUniv Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, Spain
Luaces-Regueira, Maria
[1
]
Iglesias-Garcia, Julio
论文数: 0引用数: 0
h-index: 0
机构:
Univ Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, Spain
Univ Hosp Santiago de Compostela, Dept Gastroenterol, Santiago De Compostela 15706, SpainUniv Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, Spain
Iglesias-Garcia, Julio
[1
,2
]
Lindkvist, Bjorn
论文数: 0引用数: 0
h-index: 0
机构:
Univ Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, Spain
Univ Gothenburg, Inst Med, Sahlgrenska Acad, Gothenburg, SwedenUniv Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, Spain
Lindkvist, Bjorn
[1
,3
]
Castineira-Alvarino, Margarita
论文数: 0引用数: 0
h-index: 0
机构:
Univ Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, SpainUniv Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, Spain
Castineira-Alvarino, Margarita
[1
]
Nieto-Garcia, Laura
论文数: 0引用数: 0
h-index: 0
机构:
Univ Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, SpainUniv Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, Spain
Nieto-Garcia, Laura
[1
]
Larino-Noia, Jose
论文数: 0引用数: 0
h-index: 0
机构:
Univ Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, Spain
Univ Hosp Santiago de Compostela, Dept Gastroenterol, Santiago De Compostela 15706, SpainUniv Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, Spain
Larino-Noia, Jose
[1
,2
]
Enrique Dominguez-Munoz, J.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, Spain
Univ Hosp Santiago de Compostela, Dept Gastroenterol, Santiago De Compostela 15706, SpainUniv Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, Spain
Enrique Dominguez-Munoz, J.
[1
,2
]
机构:
[1] Univ Hosp Santiago de Compostela, Fdn Res Digest Dis, Santiago De Compostela 15706, Spain
[2] Univ Hosp Santiago de Compostela, Dept Gastroenterol, Santiago De Compostela 15706, Spain
[3] Univ Gothenburg, Inst Med, Sahlgrenska Acad, Gothenburg, Sweden
Objectives Several recent studies have demonstrated the association between smoking and chronic pancreatitis (CP). However, less is known about the role of smoking in the development of CP-related complications. Our aim was to investigate the impact of smoking and alcohol consumption on age of onset and complications at CP diagnosis. Methods A cross-sectional case-case study was performed within a prospectively collected cohort of patients with CP. Alcohol consumption and smoking habits were assessed using a standardized questionnaire. Morphologic severity was defined based on endoscopic ultrasound criteria for CP and classified as mild (3-4 criteria), moderate (5-6 criteria), and severe (>= 7 criteria or calcifications). Pancreatic exocrine insufficiency (PEI) was diagnosed using the C-13-mixed triglyceride breath test. Odds ratios (OR) with 95% confidence intervals (CI) for CP-related complications were calculated using a case-case design. Results A total of 241 patients were included. Smoking was associated with PEI (OR [95% CI], 2.4 [1.17-5.16]), calcifications (OR [95% CI], 2.33 [1.10-4.95]), and severe morphologic changes (OR [95% CI], 3.41 [1.31-8.85]) but not with pseudocysts or diabetes. Neither smoking nor alcohol consumption was associated with age of onset. Conclusions Tobacco, but not alcohol, is associated with PEI, calcifications, and severe morphologic (>= 7 criteria or calcifications) CP at diagnosis. Smoking cessation should be encouraged in patients with CP.
机构:
Manchester Royal Infirm, Dept Gastroenterol, Manchester M13 9WL, Lancs, EnglandManchester Royal Infirm, Dept Gastroenterol, Manchester M13 9WL, Lancs, England
Braganza, Joan M.
;
Lee, Stephen H.
论文数: 0引用数: 0
h-index: 0
机构:
Manchester Royal Infirm, Dept Radiol, Manchester M13 9WL, Lancs, EnglandManchester Royal Infirm, Dept Gastroenterol, Manchester M13 9WL, Lancs, England
Lee, Stephen H.
;
McCloy, Rory F.
论文数: 0引用数: 0
h-index: 0
机构:
Lancashire Teaching Hosp, Dept Educ, Preston, Lancs, EnglandManchester Royal Infirm, Dept Gastroenterol, Manchester M13 9WL, Lancs, England
McCloy, Rory F.
;
McMahon, Michael J.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Leeds, Leeds, W Yorkshire, England
Nuffield Hosp, Leeds, W Yorkshire, EnglandManchester Royal Infirm, Dept Gastroenterol, Manchester M13 9WL, Lancs, England
机构:
Indiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Cote, Gregory A.
;
Yadav, Dhiraj
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Dept Med, Pittsburgh, PA USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Yadav, Dhiraj
;
Slivka, Adam
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Dept Med, Pittsburgh, PA USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Slivka, Adam
;
Hawes, Robert H.
论文数: 0引用数: 0
h-index: 0
机构:
Med Univ S Carolina, Digest Dis Ctr, Charleston, SC 29425 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Hawes, Robert H.
;
Anderson, Michelle A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Michigan, Ann Arbor, MI 48109 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Anderson, Michelle A.
;
Burton, Frank R.
论文数: 0引用数: 0
h-index: 0
机构:
St Louis Univ, Sch Med, Dept Internal Med, St Louis, MO USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Burton, Frank R.
;
Brand, Randall E.
论文数: 0引用数: 0
h-index: 0
机构:
Evanston NW Healthcare, Dept Med, Chicago, IL USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Brand, Randall E.
;
Banks, Peter A.
论文数: 0引用数: 0
h-index: 0
机构:
Brigham & Womens Hosp, Div Gastroenterol, Boston, MA 02115 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Banks, Peter A.
;
Lewis, Michele D.
论文数: 0引用数: 0
h-index: 0
机构:
Mayo Clin, Div Gastroenterol & Hepatol, Jacksonville, FL 32224 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Lewis, Michele D.
;
Disario, James A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Utah, Dept Med, Hlth Sci Ctr, Salt Lake City, UT 84112 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Disario, James A.
;
Gardner, Timothy B.
论文数: 0引用数: 0
h-index: 0
机构:
Dartmouth Hitchcock Med Ctr, Lebanon, NH 03766 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Gardner, Timothy B.
;
Gelrud, Andres
论文数: 0引用数: 0
h-index: 0
机构:
Univ Cincinnati, Dept Internal Med, Cincinnati, OH USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Gelrud, Andres
;
Amann, Stephen T.
论文数: 0引用数: 0
h-index: 0
机构:
N Mississippi Med Ctr, Tupelo, MS USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Amann, Stephen T.
;
Baillie, John
论文数: 0引用数: 0
h-index: 0
机构:
Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Baillie, John
;
Money, Mary E.
论文数: 0引用数: 0
h-index: 0
机构:
Washington Cty Hosp, Hagerstown, MD USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Money, Mary E.
;
O'Connell, Michael
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Dept Med, Pittsburgh, PA USA
Univ Pittsburgh, Dept Human Genet, Pittsburgh, PA USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
O'Connell, Michael
;
Whitcomb, David C.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Dept Med, Pittsburgh, PA USA
Univ Pittsburgh, Dept Human Genet, Pittsburgh, PA USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Whitcomb, David C.
;
Sherman, Stuart
论文数: 0引用数: 0
h-index: 0
机构:
Indiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
机构:
Univ Hosp Santiago de Compostela, Dept Gastroenterol & Hepatol, Santiago De Compostela 15706, SpainUniv Hosp Santiago de Compostela, Dept Gastroenterol & Hepatol, Santiago De Compostela 15706, Spain
机构:
Manchester Royal Infirm, Dept Gastroenterol, Manchester M13 9WL, Lancs, EnglandManchester Royal Infirm, Dept Gastroenterol, Manchester M13 9WL, Lancs, England
Braganza, Joan M.
;
Lee, Stephen H.
论文数: 0引用数: 0
h-index: 0
机构:
Manchester Royal Infirm, Dept Radiol, Manchester M13 9WL, Lancs, EnglandManchester Royal Infirm, Dept Gastroenterol, Manchester M13 9WL, Lancs, England
Lee, Stephen H.
;
McCloy, Rory F.
论文数: 0引用数: 0
h-index: 0
机构:
Lancashire Teaching Hosp, Dept Educ, Preston, Lancs, EnglandManchester Royal Infirm, Dept Gastroenterol, Manchester M13 9WL, Lancs, England
McCloy, Rory F.
;
McMahon, Michael J.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Leeds, Leeds, W Yorkshire, England
Nuffield Hosp, Leeds, W Yorkshire, EnglandManchester Royal Infirm, Dept Gastroenterol, Manchester M13 9WL, Lancs, England
机构:
Indiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Cote, Gregory A.
;
Yadav, Dhiraj
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Dept Med, Pittsburgh, PA USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Yadav, Dhiraj
;
Slivka, Adam
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Dept Med, Pittsburgh, PA USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Slivka, Adam
;
Hawes, Robert H.
论文数: 0引用数: 0
h-index: 0
机构:
Med Univ S Carolina, Digest Dis Ctr, Charleston, SC 29425 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Hawes, Robert H.
;
Anderson, Michelle A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Michigan, Ann Arbor, MI 48109 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Anderson, Michelle A.
;
Burton, Frank R.
论文数: 0引用数: 0
h-index: 0
机构:
St Louis Univ, Sch Med, Dept Internal Med, St Louis, MO USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Burton, Frank R.
;
Brand, Randall E.
论文数: 0引用数: 0
h-index: 0
机构:
Evanston NW Healthcare, Dept Med, Chicago, IL USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Brand, Randall E.
;
Banks, Peter A.
论文数: 0引用数: 0
h-index: 0
机构:
Brigham & Womens Hosp, Div Gastroenterol, Boston, MA 02115 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Banks, Peter A.
;
Lewis, Michele D.
论文数: 0引用数: 0
h-index: 0
机构:
Mayo Clin, Div Gastroenterol & Hepatol, Jacksonville, FL 32224 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Lewis, Michele D.
;
Disario, James A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Utah, Dept Med, Hlth Sci Ctr, Salt Lake City, UT 84112 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Disario, James A.
;
Gardner, Timothy B.
论文数: 0引用数: 0
h-index: 0
机构:
Dartmouth Hitchcock Med Ctr, Lebanon, NH 03766 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Gardner, Timothy B.
;
Gelrud, Andres
论文数: 0引用数: 0
h-index: 0
机构:
Univ Cincinnati, Dept Internal Med, Cincinnati, OH USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Gelrud, Andres
;
Amann, Stephen T.
论文数: 0引用数: 0
h-index: 0
机构:
N Mississippi Med Ctr, Tupelo, MS USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Amann, Stephen T.
;
Baillie, John
论文数: 0引用数: 0
h-index: 0
机构:
Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Baillie, John
;
Money, Mary E.
论文数: 0引用数: 0
h-index: 0
机构:
Washington Cty Hosp, Hagerstown, MD USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Money, Mary E.
;
O'Connell, Michael
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Dept Med, Pittsburgh, PA USA
Univ Pittsburgh, Dept Human Genet, Pittsburgh, PA USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
O'Connell, Michael
;
Whitcomb, David C.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Dept Med, Pittsburgh, PA USA
Univ Pittsburgh, Dept Human Genet, Pittsburgh, PA USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
Whitcomb, David C.
;
Sherman, Stuart
论文数: 0引用数: 0
h-index: 0
机构:
Indiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USAIndiana Univ Sch Med, Div Gastroenterol, Dept Med, Indianapolis, IN 46202 USA
机构:
Univ Hosp Santiago de Compostela, Dept Gastroenterol & Hepatol, Santiago De Compostela 15706, SpainUniv Hosp Santiago de Compostela, Dept Gastroenterol & Hepatol, Santiago De Compostela 15706, Spain