Vinylation of aryl bromides using an inexpensive vinylpolysiloxane

被引:71
作者
Denmark, SE [1 ]
Butler, CR [1 ]
机构
[1] Univ Illinois, Dept Chem, Roger Adams Lab, Urbana, IL 61801 USA
关键词
D O I
10.1021/ol052517r
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A mild and general method for the palladium-catalyzed vinylation of aryl bromides has been developed. The use of tetrabutylammonium fluoride (TBAF) as the activator and an inexpensive and nontoxic vinyl donor, 1,3,5,7-tetramethyl-1,3,5,7-tetravinylcyclotetrasiloxane (D-4(V), 1), allows for a general and high-yielding preparation of substituted styrenes.
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页码:63 / 66
页数:4
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