Molecular characterization and antifungal susceptibility of the Candida parapsilosis species complex of clinical isolates from Monterrey, Mexico

被引:22
作者
Trevino-Rangel, Rogelio De J.
Garza-Gonzalez, Elvira
Gerardo Gonzalez, J. [2 ]
Bocanegra-Garcia, Virgilio [3 ]
Llaca, Jorge M. [2 ]
Gonzalez, Gloria M. [1 ]
机构
[1] Univ Autonoma Nuevo Leon, Fac Med, Dept Microbiol, Colonia Mitras Ctr, Monterrey 64460, NL, Mexico
[2] Univ Autonoma Nuevo Leon, Fac Med, Hosp Univ, Monterrey 64460, NL, Mexico
[3] Inst Politecn Nacl, Ctr Biotecnol Genom, Lab Med Conservac, Reynosa, Tamaulipas, Mexico
关键词
Candidosis; Candida parapsilosis; Candida orthopsilosis; Candida metapsilosis; antifungal susceptibility; POPULATION-BASED SURVEILLANCE; GLOBAL SURVEILLANCE; ORTHOPSILOSIS; METAPSILOSIS; EPIDEMIOLOGY; SPP; CASPOFUNGIN; INFECTIONS; PREVALENCE; STRAIN;
D O I
10.3109/13693786.2012.675526
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Recently, it was proposed that the opportunistic yeast pathogen Candida parapsilosis was a complex composed of the following three species: Candida parapsilosis sensu stricto, Candida orthopsilosis, and Candida metapsilosis. A set of 344 clinical isolates of Candida parapsilosis from Monterrey, Mexico was re-identified by RFLP. Their antifungal susceptibility to fluconazole, caspofungin, anidulafungin and micafungin was determined using the Clinical and Laboratory Standards Institute M27-A3 protocol. Candida parapsilosis sensu stricto was the most frequent species, and was the only one which showed resistance to antifungals.
引用
收藏
页码:781 / 784
页数:4
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