Brief screening for mild cognitive impairment: validation of the Brazilian version of the Montreal cognitive assessment

被引:146
作者
Memoria, Claudia M. [1 ]
Yassuda, Monica S. [2 ]
Nakano, Eduardo Y. [3 ]
Forlenza, Orestes V. [1 ]
机构
[1] Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Lab Neurosci LIM 27, Sao Paulo, Brazil
[2] Univ Sao Paulo, Sch Arts Sci & Humanities EACH, Sao Paulo, Brazil
[3] Univ Brasilia, Dept Stat, Brasilia, DF, Brazil
关键词
MoCA; mild cognitive impairment; Alzheimer's disease; neuropsychology; cognitive assessment; neuropsychological tests; MINI-MENTAL-STATE; ALZHEIMERS-DISEASE; ASSESSMENT MOCA; VALIDITY; TOOL; PREVALENCE; DIAGNOSIS;
D O I
10.1002/gps.3787
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Background The Montreal Cognitive Assessment (MoCA) is a brief cognitive schedule that has been developed for the screening of patients with Mild Cognitive Impairment (MCI). MCI is recognized as a high-risk state for Alzheimer's disease. The aim of the present study is to examine the reliability and validity of the Brazilian version of the MoCA test (MoCA-BR) in a sample of older individuals with at least 4?years of education. Methods The MoCA-BR was administered to 112 older adults who were classified into three diagnostic groups according to their cognitive state (Alzheimer's disease, n?=?28; MCI, n?=?43; normal controls, n?=?41). This procedure was based on clinical and neuropsychological data. The performance in the MoCA-BR was compared with the Mini-mental state examination (MMSE) and the Cambridge Cognitive Examination. Diagnostic accuracy was examined with the receiver operating characteristic (ROC) curve analyses. Results Cronbach's alpha for the MoCA-BR was 0.75. Temporal stability (retesting after 3?months) using intraclass correlation coefficient was 0.75 (p?<?0.001). The sensitivity and specificity of the MoCA-BR for MCI were 81% and 77%, respectively, with a cut-off score of 25 points. The area under the ROC curve for predicting MCI was 0.82?+/-?0.06. Conclusions The present results indicate that the MoCA-BR maintains its core diagnostic properties rendering it a valid and reliable tool for the screening of MCI among older individuals with at least 4?years of education. Copyright (c) 2012 John Wiley & Sons, Ltd.
引用
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页码:34 / 40
页数:7
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