Microwave-assisted clean synthesis of xanthenes and chromenes in [bmim][PF6] and their antioxidant studies

被引：30

作者：

Iniyavan, P. ^{[1
]}

Sarveswari, S. ^{[1
]}

Vijayakumar, V. ^{[1
]}

机构：

[1] VIT Univ, Ctr Organ & Med Chem, Vellore 632014, Tamil Nadu, India

来源：

RESEARCH ON CHEMICAL INTERMEDIATES | 2015年 / 41卷 / 10期

关键词：

Xanthenes; Chromenes; Ionic liquid; Antioxidant activity; ULTRASOUND-PROMOTED SYNTHESIS; ONE-POT; IONIC LIQUID; IN-VITRO; DERIVATIVES; EFFICIENT; CATALYST; 1,4-DIHYDROPYRIDINES; BI;

D O I：

10.1007/s11164-014-1821-4

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient one-pot synthesis of xanthene and chromene derivatives by three-component reactions of aryl aldehydes, cyclic 1,3-diketones, and 2-naphthol/4-hydroxy coumarin catalyzed by ionic liquid (IL) [bmim][PF6] under microwave irradiation is described. The present scheme provides several advantages such as short reaction time, mild reaction conditions, good yields, convenient operation, and reuse of IL. In vitro antioxidant activity was evaluated for the synthesized compounds by DPPH method. Compounds 6a, 6h, 6c, 6b, 4k, and 4a showed the highest antioxidant potency.

引用

页码：7413 / 7426

页数：14

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