Synthesis of Conjugated Dienes via a Biomimetic Aerobic Oxidative Coupling of Two CvinylH Bonds

被引：66

作者：

Gigant, Nicolas ^{[1
]}

Backvall, Jan-E. ^{[1
]}

机构：

[1] Stockholm Univ, Dept Organ Chem, Arrhenius Lab, S-10691 Stockholm, Sweden

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2013年 / 19卷 / 33期

基金：

欧洲研究理事会;

关键词：

aerobic oxidation; biomimetic synthesis; CH activation; conjugated dienes; cross-coupling; C-H FUNCTIONALIZATION; DEHYDROGENATIVE ALKENYLATION; LINEAR 1,3-BUTADIENES; AROMATIC SUBSTITUTION; SELECTIVE ACCESS; NATURAL-PRODUCTS; OLEFINATION; ACTIVATION; EFFICIENT; ARYLATION;

D O I：

10.1002/chem.201301771

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A time to dienes: A highly efficient and general method has been developed to prepare conjugated dienes through a biomimetic approach. This aerobic oxidative coupling, involving two Cvinyl-H bonds, proceeds under low Pd catalyst loading and employs catalytic amounts of p-benzoquinone and iron phthalocyanine as electron-transfer mediators (ETMs) under ambient oxygen pressure (see scheme). © 2013 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：10799 / 10803

页数：5