Visible light-induced green synthesis of 2-amino-4H-chromenes

被引：20

作者：

Chen, Lu ^{[1
]}

Lin, Chuyuan ^{[1
]}

Lan, Yongyin ^{[1
]}

Li, Zhenzhen ^{[1
]}

Huang, Dandan ^{[1
]}

Yang, Wei ^{[2
]}

Li, Yibiao ^{[1
]}

机构：

[1] Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen, Peoples R China

[2] Guangzhou Univ, Sch Chem & Chem Engn, Guangzhou, Peoples R China

来源：

ENVIRONMENTAL CHEMISTRY LETTERS | 2020年 / 18卷 / 06期

关键词：

Green synthesis; Photocatalysis; Multicomponent reaction; Chromenes; Phenol moieties; Six member O-heterocycles; BIOLOGICAL EVALUATION; HIGHLY EFFICIENT; CATALYST; DERIVATIVES; BISCOUMARIN; ANALOGS;

D O I：

10.1007/s10311-020-01053-2

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Green chemistry aims at developing reactions that are cheap, clean and use less energy. For that, multicomponent reactions are drawing attention, yet, actual methods involve complicated work-ups, hazardous solvents, toxic catalysts, high catalyst loads, harsh reaction conditions and tedious catalyst preparation. Here, we demonstrate that the commercially available reagent, 9-mesityl-10 methylacridinium perchlorate (Acr(+)-Mes ClO4-), can serve as a photocatalyst in the presence of a blue lamp light source, promoting the synthesis of 2-amino-4H-chromenes via a multicomponent reaction with low catalyst loadings. A wide range of aromatic aldehydes readily undergo condensation with malononitrile and ArOH-type structural motifs under mild conditions to afford the products in 76-95% yield within 60 min.

引用

页码：2157 / 2163

页数：7

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