Rasburicase for Huge Hepatocellular Carcinoma with Tumor Lysis Syndrome: Case Report

被引：7

作者：

Chao, Chia-Ter ^{[1
]}

Chiang, Chih-Kang ^{[1
]}

机构：

[1] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Internal Med, Div Nephrol,Coll Med, Taipei 100, Taiwan

来源：

MEDICAL PRINCIPLES AND PRACTICE | 2012年 / 21卷 / 05期

关键词：

Hepatocellular carcinoma; Tumor lysis syndrome; Rasburicase; Uric acid; Acute kidney injury; TRANSARTERIAL CHEMOEMBOLIZATION; SORAFENIB; PATIENT;

D O I：

10.1159/000339083

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective: To report a case of huge hepatocellular carcinoma associated with tumor lysis syndrome and its management. Clinical Presentation and Intervention: A 51-year-old hepatitis B carrier visited our clinic with progressive weight loss over recent months. Abdominal ultrasonography and magnetic resonance imaging revealed a huge hepatic mass in a cirrhotic liver, identified as hepatocellular carcinoma. A hepatologist and surgeon recommended transarterial chemoembolization followed by hepatectomy. The patient underwent the procedure, with the complication of tumor lysis syndrome. He was treated with a single high dose (9 mg) of rasburicase and his clinical condition improved dramatically, with acute kidney injury subsiding without emergent hemodialysis. Conclusions: This was a case of hepatocellular carcinoma with tumor lysis syndrome and acute kidney injury, treated successfully with rasburicase. Copyright (c) 2012 S. Karger AG, Basel

引用

页码：498 / 500

页数：3

共 10 条

[1] Acute tumor lysis syndrome after transcatheter chemoembolization of hepatocellular carcinoma [J].