Bioactive chemical constituents of Caesalpinia bonduc (Fabaceae)

被引：38

作者：

Ata, Athar ^{[1
]}

Gale, Elikana M. ^{[1
]}

Samarasekera, Radhika ^{[2
]}

机构：

[1] Univ Winnipeg, Dept Chem, Winnipeg, MB R3B 2E9, Canada

[2] Ind Technol Inst, Nat Prod Dev Grp, Colombo, Sri Lanka

来源：

PHYTOCHEMISTRY LETTERS | 2009年 / 2卷 / 03期

基金：

加拿大自然科学与工程研究理事会;

关键词：

Caesalpinia bonduc (Fabaceae); Glutathione S-transferase; Caesalpinianone; 6-O-Methylcaesalpinianone; FURANODITERPENES;

D O I：

10.1016/j.phytol.2009.02.002

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Phytochemical studies on the ethanolic extracts of Caesalpinia bonduc (Fabaceae) yielded two new homoisoflavonoids, caesalpinianone, and 6-O-methylcaesalpinianone along with five known natural products, namely, hematoxylol, stereochenol A, 6'-O-acetylloganic acid, 4'-O-acetylloganic acid, and 2'-beta-D-glucosyloxy-4-methoxybenzenepropanoic acid. Structures of these compounds were elucidated with the aid of extensive NMR spectral studies. All of these compounds exhibited different levels of glutathione S-transferase (GST) inhibitory and antifungal activities. (C) 2009 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

引用

页码：106 / 109

页数：4

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