Bioactive chemical constituents of Caesalpinia bonduc (Fabaceae)

被引:38
|
作者
Ata, Athar [1 ]
Gale, Elikana M. [1 ]
Samarasekera, Radhika [2 ]
机构
[1] Univ Winnipeg, Dept Chem, Winnipeg, MB R3B 2E9, Canada
[2] Ind Technol Inst, Nat Prod Dev Grp, Colombo, Sri Lanka
基金
加拿大自然科学与工程研究理事会;
关键词
Caesalpinia bonduc (Fabaceae); Glutathione S-transferase; Caesalpinianone; 6-O-Methylcaesalpinianone; FURANODITERPENES;
D O I
10.1016/j.phytol.2009.02.002
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Phytochemical studies on the ethanolic extracts of Caesalpinia bonduc (Fabaceae) yielded two new homoisoflavonoids, caesalpinianone, and 6-O-methylcaesalpinianone along with five known natural products, namely, hematoxylol, stereochenol A, 6'-O-acetylloganic acid, 4'-O-acetylloganic acid, and 2'-beta-D-glucosyloxy-4-methoxybenzenepropanoic acid. Structures of these compounds were elucidated with the aid of extensive NMR spectral studies. All of these compounds exhibited different levels of glutathione S-transferase (GST) inhibitory and antifungal activities. (C) 2009 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:106 / 109
页数:4
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