Peptide Derivatives as Agonists or Antagonists of Formylpeptide Receptors: Analysis of their Effects on Neutrophils

被引：2
作者：
Dalpiaz, Alessandro [1 ]
Scatturin, Angelo [1 ]
机构：
[1] Dipartimento Sci Farmaceut, Via Fossato Mortara 19, I-44100 Ferrara, Italy
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2003年 / 3卷 / 03期
关键词：
Formyl-peptide receptor; Neutrophil; Inflammation; Chemotaxis; G-protein coupled receptor; AIDS/HIV; Agonist; Antagonist;
D O I：
10.2174/1389557033488222
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The effects of peptide derivatives as agonists or antagonists of formylpeptide receptors are described, taking into account the related cellular responses by neutrophils. These effects are related to the structure of peptide derivatives, some of which are potent anti HIV-1 agents. Finally, formylpeptide receptor models are depicted.
引用
收藏
页码：167 / 173
页数：7
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